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Electrochemical Sensing of Anticancer Drug Using New Electrocatalytic Approach

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Abstract

Cancer is one of the leading causes of death worldwide. It is very important to regulate drug doses for cancer patients in the treatment of cancer with drugs. Determination of drugs used as anticancer at low concentrations and determination of them with high sensitivity is of great importance for the follow-up of these drugs. Electrochemical techniques offer a wide variety of detection techniques that provide user-friendly, low-cost, and real-time monitoring compared to other conventional methods and provide low sensitivity and detection limits. By modifying the electrode surfaces with various materials, their sensitivity and detection limits can be increased. This review focuses on new electrocatalytic approaches and current developments for the electrochemical determination of anticancer drugs. In addition, anticancer drugs are classified in detail. Electrochemical sensors used in studies in recent years and verification parameters such as detection limit, linear dynamic range, sensitivity are given in tables.

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Abbreviations

AdSDPV:

Adsorptive stripping differential pulse voltammetry

Ag:

Silver

AgNCs:

Silver nanocubes

AuNPs:

Gold nanoparticles

CNTs:

Carbon nanotubes

CPE:

Carbon paste electrode

CV:

Cyclic voltammetry

DPV:

Differential pulse voltammetry

EIS:

Electrochemical impedance spectroscopy

FE-SEM:

Field emission scanning electron microscopy

FLU:

Flutamide

GC–MS:

Mass spectrometry–dependent gas chromatography

LC–MS:

Mass spectrometry–dependent liquid chromatography

LOD:

Limit of detection

MIP:

Molecularly imprinted polymer

MOFs:

Metal–organic frameworks

MoS2 :

Molybdenum disulfide

MWCNT:

Multi-walled carbon nanotube

NSCLC:

Non-small cell lung cancer

PGNR:

Porous graphene nanoribbon

SCLC:

Small cell lung cancer

SEM:

Scanning electron microscopy

SPCE:

Screen-printed carbon electrode

SWV:

Square wave voltammetry

SWCNT:

Single-walled carbon nanotube

ZnMn2O4-PGO:

ZnMn2O4 nanoparticles decorated porous reduced graphene oxide nanocomposite

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Acknowledgements

Ahmet Cetinkaya thanks the financial supports from the Council of Higher Education 100/2000 (YOK) under the special 100/2000 and the Scientific and Technological Research Council of Turkey (TÜBITAK) under the BIDEB/2211-A Ph.D. Scholarship Programmes.

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Authors and Affiliations

  1. Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey

    Ahmet Cetinkaya, Leyla Karadurmus, S. Irem Kaya, Goksu Ozcelikay & Sibel A. Ozkan

  2. Department of Analytical Chemistry, Faculty of Pharmacy, Adıyaman University, Adiyaman, Turkey

    Leyla Karadurmus

  3. Department of Analytical Chemistry, Gulhane Faculty of Pharmacy, University of Health Sciences, Ankara, Turkey

    S. Irem Kaya

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  1. Ahmet Cetinkaya
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  2. Leyla Karadurmus
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  3. S. Irem Kaya
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  4. Goksu Ozcelikay
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  5. Sibel A. Ozkan
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Correspondence to Sibel A. Ozkan.

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Cetinkaya, A., Karadurmus, L., Kaya, S.I. et al. Electrochemical Sensing of Anticancer Drug Using New Electrocatalytic Approach. Top Catal 65, 703–715 (2022). https://doi.org/10.1007/s11244-021-01536-8

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