Skip to main content
SpringerLink
Log in

Complex formation reactions of two sterically hindered platinum(II) complexes with some N-bonding ligands

  • Published:
Transition Metal Chemistry Aims and scope Submit manuscript

Abstract

The kinetics of the complex formation reactions of two [(TLtBu)PtCl]+ and [Pt(tpdm)Cl]+ complexes (TLtBu = 2,6-bis[(1,3-di-tert-butylimidazolin-2-imino)methyl]pyridine and tpdm = terpyridinedimethane) with N-donor ligands, l-histidine (L-His), inosine (Ino), inosine-5′-monophosphate (5′-IMP) and guanosine-5′-monophosphate (5′-GMP), were studied. All reactions were studied under pseudo-first-order conditions as a function of nucleophile concentration and temperature in aqueous 0.1 M NaClO4 solution in the presence of 10 mM NaCl using variable-temperature Uv–Vis spectrophotometry. The order of reactivity of the studied ligands is L-His > Ino > 5′-GMP > 5′-IMP. This order of reactivity is in relation to their electronic properties and structures. The mechanism of the substitution reactions is associative in nature as supported by the negative entropy of activation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

Abbreviations

TLtBu :

2,6-bis[(1,3-di-tert-butylimidazolin-2-imino)methyl]pyridine

Tpdm:

Terpyridinedimethane

References

  1. Lippert B (1999) Cisplatin, chemistry and biochemistry of leading antitumor drugs. Wiley-VCH, Zuruch, pp 183–221

    Book  Google Scholar 

  2. Alessio E (2011) Bioinorganic medicinal chemistry. Wiley-VCH, Weinheim Chapters 1–4

    Book  Google Scholar 

  3. Reedijk J (2011) Pure Appl Chem 83:1709–1719

    Article  CAS  Google Scholar 

  4. Butler JS, Sadler PJ (2013) Cur Opin Chem Biol. doi:10.1016/j.cbpa.2013.01.004

  5. Jakupec MA, Galanski M, Arion VB, Hartinger CG, Keppler BK (2008) Dalton Trans 2:183

    Article  Google Scholar 

  6. Bruijnincx PCA, Sadler PJ (2009) Adv Inorg Chem 61:1–62

    Article  CAS  Google Scholar 

  7. Bugarčić ŽD, Bogojeski J, Petrović B, Hochreuther S, van Eldik R (2012) Dalton Trans 41:12329–12636

    Article  Google Scholar 

  8. Bugarčić ŽD, Heinemann FW, van Eldik R (2004) Dalton Trans 279–286

  9. Soldatović T, Bugarčić ŽD (2005) J Inorg Biochem 99:1472–1479

    Article  Google Scholar 

  10. Bugarčić ŽD, Rosić J, Petrović B, Summa N, Puchta R, van Eldik R (2007) J Biol Inorg Chem 12:1141–1150

    Article  Google Scholar 

  11. Petrović B, Bugarčić ŽD, Dees A, Ivanović-Burmazović I, Heinemann F, Puchta R, van Eldik R (2011) Inorg Chem 51:1516–1529

    Article  Google Scholar 

  12. Bogojeski J, Jelić R, Petrović D, Herdtweck E, Jones PG, Tamm M, Bugarčić ŽD (2011) Dalton Trans 40:6515–6523

    Article  CAS  Google Scholar 

  13. Đurović M, Bogojeski J, Petrović B, Petrović D, Heinemann FW, Bugarčić ŽD (2012) 41:70–76

  14. Mijatović A, Bogojeski J, Petrović B, Bugarčić ŽD (2012) Inorg Chem Acta 283:300–304

    Article  Google Scholar 

  15. Selimović E, Petrović B, Čanović D, Bugarčić ŽD, Bogojeski J (2013) Aust J Chem. doi:10.1071/CH12218

  16. Tobe ML, Burgess J (1991) Inorganic reaction mechanisms. Addison Wesley Longman, Essex Chapter 3

    Google Scholar 

  17. Perutz M (1970) Nature 228:726–734

    Article  CAS  Google Scholar 

  18. Tainer JA, Getzoff ED, Beem KM, Richardson JS, Richardson DC (1982) J Mol Biol 160:181–217

    Article  CAS  Google Scholar 

  19. Arpalahti J, Lehikoinen P (1990) Inorg Chem 29:2564–2567

    Article  CAS  Google Scholar 

  20. Arpalahti J, Lippert B (1990) Inorg Chem 29:104–110

    Article  CAS  Google Scholar 

  21. Caradonna JP, Lippard SJ Inorg Chem 27:1454–1466

  22. Mikola M, Kilika KD, Arpalahti J (2000) Chem Eur J:3404–3413

  23. Bugarčić ŽD, Soldatović T, Jelić R, Alguero B, Grandas A (2004) Dalton Trans:3869–3877

  24. Rau T, van Eldik R (1997) Inorg Chem 36:1454–1463

    Article  CAS  Google Scholar 

  25. Prinsloo FF, JPienaar JJ, van Eldik R (1995) J Chem Soc Dalton Trans:3581–3589

  26. Hofmann A, Jaganyi D, Munro QO, Liehr G, van Eldik R (2003) Inorg Chem 42:1688–1700

    Article  CAS  Google Scholar 

  27. Jaganyi D, Hofmann A, van Eldik R (2001) Angew Chem Int Ed Engl 40:1680–1683

    Article  CAS  Google Scholar 

  28. Petrović D, Stojimirović B, Petrović B, Bugarčić ZM, Bugarčić ŽD (2007) Bioorgan Med Chem 15:4203–4211

    Article  Google Scholar 

  29. Petrović D, Hill LMR, Jones PG, Tolman WB, Tamm M (2008) Dalton Trans:887–894

  30. Vedernikov AN, Huffman JC, Caulton KG (2002) Inorg Chem 41:6244–6248

    Article  CAS  Google Scholar 

  31. Appleton TG, Hall JR, Ralph SF, Thompson CSM (1984) Inorg Chem 23:3521–3525

    Article  CAS  Google Scholar 

Download references

Acknowledgments

The authors gratefully acknowledge financial support from the Ministry of Education, Science and Technological Development of the Republic of Serbia, Project No. 172011.

Author information

Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Kragujevac, R. Domanovića 12, P. O. Box 60, 34000, Kragujevac, Serbia

    Enisa Selimović, Biljana Petrović, Živadin D. Bugarčić & Jovana Bogojeski

  2. Faculty of Medicine, University of Kragujevac, S. Markovića 69, 34000, Kragujevac, Serbia

    Tatjana Vulović

Authors
  1. Enisa Selimović
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tatjana Vulović
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Biljana Petrović
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Živadin D. Bugarčić
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jovana Bogojeski
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jovana Bogojeski.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 25 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Selimović, E., Vulović, T., Petrović, B. et al. Complex formation reactions of two sterically hindered platinum(II) complexes with some N-bonding ligands. Transition Met Chem 38, 635–640 (2013). https://doi.org/10.1007/s11243-013-9731-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11243-013-9731-7

Keywords

Search

Navigation