Abstract
The oxidation of tyrosine by chromium(VI) in aqueous perchloric acid medium has been studied spectrophotometrically at 30 °C and at a constant ionic strength I = 3.10 mol dm−3. The main reaction products were identified as chromium(III) and 4-hydroxyphenylacetaldehyde. The stoichiometry is 2:3, i.e., two moles of chromium(VI) react with three moles of tyrosine. The reaction is first order with respect to both chromium(VI) and tyrosine. Increase in perchloric acid concentration increased the rate of reaction. The order with respect to acid concentration was found to be two. Added products, ionic strength and dielectric constant of the medium did not have any significant effect on the reaction rate. A suitable mechanism is proposed. The activation parameters were determined with respect to the slow step of the mechanism. The thermodynamic quantities were also determined and discussed.
Similar content being viewed by others
References
(a) Chimatadar SA, Koujalagi SB, Nandibewoor ST (2001) Transition Met Chem 26:662; (b) Wiberg KB (1965) Oxidation in organic chemistry. Academic Press, New York, Part A, p 69
(a) Chimatadar SA, Basavaraj T, Nandibewoor ST (2006) Polyhedron 25:2976; (b) Day MC Jr, Selbin J (1964) Theoretical inorganic chemistry. Reinhold Publishing Corporation, New York, p 226
Chimatadar SA, Salunke MS, Nandibewoor ST (2006) Indian J Chem 45A:338
Jeffery GH, Bassett J, Mendham J, Denney RC (1996) Vogel’s textbook of quantitative chemical analysis, 5th edn. ELBS, Longman, Essex, England (a) p 375, (b) p 195
Das AK, Das M (1994) J Chem Soc Dalton Trans 589
(a) Wiberg KB, Lepse PA (1964) J Am Chem Soc 86:2612; (b) Best PA, Littler JS, Waters WA (1962) J Chem Soc 822; (c) Hasan F, Rocek J (1975) J Am Chem Soc 19:1448
(a) Chimatadar SA, Salunke MS, Nandibewoor ST (2006) Indian J Chem 45A:338; (b) Chimatadar SA, Koujalagi SB, Nandibewoor ST (2004) Oxid Commun 27:81; (c) Mason JG, Kowalak AD (1964) Inorg Chem 3:1248
(a) Rahaman M, Rocek J (1971) J Am Chem Soc 93:5462; (b) Chimatadar SA, Koujalagi SB, Nandibewoor ST (2002) Transition Met Chem 27:704
Rangappa KS, Ragavendra MP, Mahadevappa DS, Channegouda D (1966) J Org Chem 63:421
Weissberger (ed) (1974) Investigation of rates and mechanism of reactions intechniques of chemistry. Lewis ES, Wiley, Interscience Publication, New York, p 421
(a) Martinez M, Pitarque MA, Eldik RV (1996) J Chem Soc Dalton Trans 2665; (b) Farokhi SA, Nandibewoor ST (2003) Tetrahedron 59:7595
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Naik, P.N., Chimatadar, S.A. & Nandibewoor, S.T. A kinetic and mechanistic study of the oxidation of tyrosine by chromium(VI) in aqueous perchloric acid medium. Transition Met Chem 33, 405–410 (2008). https://doi.org/10.1007/s11243-007-9050-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11243-007-9050-y