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Carboxy Ester Hydrolysis Promoted by Two New Bimetallic Macrocyclic Complexes. Synthesis, Characterization and Catalytic Activity


A dinuclear macrocyclic ligand containing [12]aneN3 and its two transition metal complexes, [Zn2L(OAc)2](ClO4)2 (1) and [Cu2L(OAc)2](ClO4)2 (2) have been synthesized and characterized on the basis of elemental analyses, molar conductivities, 1H-n.m.r, IR spectra, electronic spectra and thermal analysis. In addition, the studies on the hydrolysis of a caboxy ester, 4-nitrophenyl acetate (NA), promoted by the two complexes were also investigated. The experimental results indicated that the two complexes can efficiently catalyze hydrolysis of NA, and the kNA for complexes (1) and (2) at pH 7.25, 25 °C, were calculated to be 4.46 × 10−2 and 4.21 × 10−2 m−1 s−1, respectively, which are better than those of the corresponding mononuclear complex in the same conditions.

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  1. D.E. Wilcox (1996) Chem. Rev. 96 2435 Occurrence Handle1:CAS:528:DyaK28Xmt1Gnu7s%3D Occurrence Handle10.1021/cr950043b

    CAS  Article  Google Scholar 

  2. J.A. Cowan (1998) Chem. Rev. 98 1067 Occurrence Handle1:CAS:528:DyaK1cXis12iu7c%3D Occurrence Handle10.1021/cr960436q

    CAS  Article  Google Scholar 

  3. B. Chevrier C. Schalk H. Dorchymont J. Rondeau D. Moras C. Tarnus (1994) Structure 2 283 Occurrence Handle1:CAS:528:DyaK2MXhslyksQ%3D%3D Occurrence Handle10.1016/S0969-2126(00)00030-7

    CAS  Article  Google Scholar 

  4. J.L. Vanhooke M.M. Benning F.M. Raushel H.V. Holden (1996) Biochemistry 35 6020 Occurrence Handle1:CAS:528:DyaK28XisVylsrg%3D Occurrence Handle10.1021/bi960325l

    CAS  Article  Google Scholar 

  5. E. Hough L.K. Hansen B. Birknes K. Jynge S. Hansen A. Hordvik C. Little E. Dodson Z. Derewenda (1989) Nature 338 360 Occurrence Handle10.1038/338357a0

    Article  Google Scholar 

  6. G.C. Silver W.C. Trogler (1995) J. Am. Chem. Soc. 117 3983 Occurrence Handle1:CAS:528:DyaK2MXkvVWrsbo%3D Occurrence Handle10.1021/ja00119a013

    CAS  Article  Google Scholar 

  7. J.A. Halfen J. Yong W.B. Tolman (1996) J. Am. Chem. Soc. 118 10920 Occurrence Handle1:CAS:528:DyaK28Xmt1Gmuro%3D Occurrence Handle10.1021/ja962344o

    CAS  Article  Google Scholar 

  8. L.J. Farrugia, P.A. Lovatt and R.D. Peacock, J. Chem. Soc. Dalton Trans., 911 (1997)

  9. E. Kimura M. Shionoya T. Koike I. Nakamura Y. Kodama (1994) J. Am. Chem. Soc. 116 4764 Occurrence Handle1:CAS:528:DyaK2cXltVaqsro%3D Occurrence Handle10.1021/ja00090a024

    CAS  Article  Google Scholar 

  10. E. Kimura and K.D. Karlin, Progress in Inorganic Chemistry (Ed) , Vol. 41, Wiley, New York, 1993, p. 443

  11. R.W. Alder, R.W. Mowlam, D.J. Vachon and G.R. Weisman, J.Chem.Soc. Chem.Commun., 507 (1992)

  12. S.A. Li D.X. Xia Y. Yang D.F. Li M.F. Wu W.X. Tang (2002) Inorg, Chem. 41 1807 Occurrence Handle1:CAS:528:DC%2BD38Xhsl2ntrY%3D Occurrence Handle10.1021/ic011019l

    CAS  Article  Google Scholar 

  13. S.A. Li D.X. Xia Y. Yang D.F. Li J. Huang W.X. Tang (2002) New. J. Chem. 26 1831 Occurrence Handle1:CAS:528:DC%2BD38XovVelsLc%3D Occurrence Handle10.1039/b205302k

    CAS  Article  Google Scholar 

  14. J. Huang D.F. Li S.A. Li D.X. Yang W.Y. Sun W.X. Tang (2004) J. Inorg. Biochem. 98 502 Occurrence Handle1:CAS:528:DC%2BD2cXhsV2kurY%3D Occurrence Handle10.1016/j.jinorgbio.2003.12.016

    CAS  Article  Google Scholar 

  15. R. Gary, D.J. Weisman and V.B. Vachon, J.Chem. Soc.Chem.Commun., 886 (1987)

  16. T.J. Atkins (1980) J. Am. Chem. Soc. 102 6364 Occurrence Handle1:CAS:528:DyaL3MXjvFyj Occurrence Handle10.1021/ja00540a044

    CAS  Article  Google Scholar 

  17. G.R. Weisman V. Johnson R.E. Fiala (1980) Tetrahedron Lett. 37 3635 Occurrence Handle10.1016/S0040-4039(00)78731-4

    Article  Google Scholar 

  18. T.J. Atkins J.E. Richman W.F. Oettle (1978) Org. Synth. 58 86 Occurrence Handle1:CAS:528:DyaL3cXltlant7k%3D

    CAS  Google Scholar 

  19. W.J. Geary (1971) Coord. Chem. Rev. 7 110 Occurrence Handle10.1016/S0010-8545(00)80009-0

    Article  Google Scholar 

  20. Z.Y. Yang R.D. Yang Q. Li F.S. Li (1999) Synth. React. Inorg. Met-Org Chem. 29 205 Occurrence Handle1:CAS:528:DyaK1MXhtlyjtbc%3D

    CAS  Google Scholar 

  21. Z.Y. Yang (2002) Synth. React. Inorg. Met-Org Chem. 32 903 Occurrence Handle1:CAS:528:DC%2BD38XlsFKktr0%3D Occurrence Handle10.1081/SIM-120013146

    CAS  Article  Google Scholar 

  22. F. Marchetti C. Pettinari R. Pettinari D. Leonesi A. Lorenzotti (1999) Polyhydron 18 3041 Occurrence Handle1:CAS:528:DyaK1MXnsVGnt7k%3D Occurrence Handle10.1016/S0277-5387(99)00230-2

    CAS  Article  Google Scholar 

  23. G.B. Deacon R.J. Phillips (1980) Coord. Chem. Rev. 33 227 Occurrence Handle1:CAS:528:DyaL3MXjvVOqsw%3D%3D Occurrence Handle10.1016/S0010-8545(00)80455-5

    CAS  Article  Google Scholar 

  24. J. Reim, B. and J. Krebs, J. Chem. Soc. Dalton Trans., 3793 (1997)

  25. K. Nakamoto (1978) Infrared and Raman Spectra of Inorganic and Coordination Compounds EditionNumber3 Wiley New York

    Google Scholar 

  26. J. Xia Y. Xu S.A. Li W.Y. Sun K.B. Yu W.X. Tang (2001) Inorg Chem. 40 2394 Occurrence Handle1:CAS:528:DC%2BD3MXis1Sltr8%3D Occurrence Handle10.1021/ic000642n

    CAS  Article  Google Scholar 

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Ren, YW., Guo, H., Wang, C. et al. Carboxy Ester Hydrolysis Promoted by Two New Bimetallic Macrocyclic Complexes. Synthesis, Characterization and Catalytic Activity. Transition Met Chem 31, 611–615 (2006).

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  • EtOH
  • Mononuclear Complex
  • Macrocyclic Ligand
  • Phenyl Phosphate
  • Guanidinium Salt