Skip to main content
SpringerLink
Log in

Increased risk of heparin induced thrombocytopenia and thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation

  • Letter to the Editor
  • Published:
Journal of Thrombosis and Thrombolysis Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Castelli R, Gallipoli P, Schiavon R, Teatini T, Deliliers GL, Bergamaschini L (2018) High prevalence of heparin induced thrombocytopenia with thrombosis among patients with essential thrombocytemia carrying V617F mutation. J Thromb Thrombolysis 45(1):106–113. https://doi.org/10.1007/s11239-017-1566-1

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Antonioli E, Guglielmelli P, Poli G et al (2008) Influence of JAK2V617F allele burden on phenotype in essential thrombocythemia. Haematologica 93(1):41–48. https://doi.org/10.3324/haematol.11653

    Article  CAS  PubMed  Google Scholar 

  3. Vannucchi AM, Antonioli E, Guglielmelli P et al (2007) Clinical profile of homozygous JAK2 617V> F mutation in patients with polycythemia vera or essential thrombocythemia. Blood 110(3):840–846. https://doi.org/10.1182/blood-2006-12-064287

    Article  CAS  PubMed  Google Scholar 

  4. Colombo R, Gallipoli P, Castelli R (2014) Thrombosis and hemostatic abnormalities in hematological malignancies. Clin Lymphoma Myeloma Leuk 14(6):441–450

    Article  PubMed  Google Scholar 

  5. Castelli R, Ferrari B, Cortelezzi A, Guariglia A (2010) Thromboembolic complications in malignant haematological disorders. Curr Vasc Pharmacol 4:482–494

    Article  Google Scholar 

  6. De Stefano V, Za T, Rossi E et al (2010) Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation. Ann Hematol 89(2):141–146. https://doi.org/10.1007/s00277-009-0788-5

    Article  CAS  PubMed  Google Scholar 

  7. De Stefano V, Za T, Rossi E et al (2009) Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia. Haematologica 94(5):733–737. https://doi.org/10.3324/haematol.13869

    Article  PubMed  PubMed Central  Google Scholar 

  8. Takahaski K, Patel P (2013) V617F detection and allele burden measurement in peripheral blood and bone marrow aspirate in patients with myeloproliferative neoplasms. Blood 122(23):3784–3786

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biomedical and Clinical Sciences Luigi Sacco, Luigi Sacco Hospital, University of Milan, Milan, Italy

    Roberto Castelli, Riccardo Schiavon, Thomas Teatini & Luigi Bergamaschini

  2. Department of Haematology, Cambridge Institute for Medical Research, Cambridge University, Cambridge, UK

    Paolo Gallipoli

  3. Fondazione Matarelli Milano, Milan, Italy

    Giorgio Lambertenghi Deliliers

Authors
  1. Roberto Castelli
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Paolo Gallipoli
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Riccardo Schiavon
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Thomas Teatini
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Giorgio Lambertenghi Deliliers
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Luigi Bergamaschini
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Roberto Castelli.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Castelli, R., Gallipoli, P., Schiavon, R. et al. Increased risk of heparin induced thrombocytopenia and thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation. J Thromb Thrombolysis 47, 155–156 (2019). https://doi.org/10.1007/s11239-018-1773-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11239-018-1773-4

Search

Navigation