Abstract
Kimura disease (KD) is an angiolymphoid proliferative disorder of unknown etiology, occurs mainly in Asian patients, presenting with subcutaneous slowly growing masses, with a predilection for preauricular and submandibular regions. The clinical course of the disease is thought to be benign. Concomitant peripheral blood eosinophilia and elevated serum immunoglobulin E levels are often observed. Main systemic manifestation of the KD is renal involvement. Renal abnormalities, notably proteinuria and nephrotic syndrome have been found to be associated with KD. We report a 42-year-old man with KD and a steroid-sensitive membraneous nephrotic syndrome with bilaterally temporal artery and renal vein thrombosis. This is the first reported case of KD associated nephrotic syndrome complicated with wide arterial and venous thrombosis from Anatolia.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Abuel-Haija M, Hurford MT (2007) Kimura disease. Arch Pathol Lab Med 131(4):650–651
Wang TF, Liu SH, Kao CH, Chu SC, Kao RH, Li CC (2006) Kimura’s disease with generalized lymphadenopathy demonstrated by positron emission tomography scan. Intern Med 45 (12):775–778
Deshpande AH, Nayak S, Munshi MM, Bobhate SK (2002) Kimura’s disease. Diagnosis by aspiration cytology. Acta Cytol 46(2):357–363
Lee CY, Su CY, Sheen-Chen SM, Eng HL, Chen WJ (1994) Kimura’s disease – report of four cases. Changgeng Yi Xue Za Zhi 17(2):153–157
Matsuda O, Makiguchi K, Ishibashi K et al (1992) Long-term effects of steroid treatment on nephrotic syndrome associated with Kimura’s disease and a review of the literature. Clin Nephrol 37:119–123
Yamada A, Mitsuhashi K, Miyakawa Y et al (1982) Membranous glomerulonephritis associated with eosinophilic lymph folliculosis of the skin (Kimura’s disease): report of a case and review of the literature. Clin Nephrol 18:211–215
Senel MF, Buren CT, Etheridge WB, Barcenas C, Jammal C, Kahan BD (1996) Effects of cyclosporine, azathioprine and prednisone on Kimura’s disease and focal segmental glomerulosclerosis in renal transplant patients. Clin Nephrol 45:18–21
Lu HJ, Tsai JD, Sheu JC, Tzen CY, Tsai TC, Lin CC, Huang FY (2003) Kimura disease in a patient with renal allograft failure secondary to chronic rejection. Pediatr Nephrol 18(10):1069–1072
Konishi N, Tamura T, Kawai C, Shirai T (1981) IgE associated nephropathy in a patient with subcutaneous eosinophilic lymphoid granuloma (Kimura’s disease). Virchows Arch Path Anat 392:127–134
UpTodate 15/2 Renal vein thrombosis and hypercoagulability in nephrotic syndrome
Tarry WC, Moser AJ, Makhoul RG (1993) Peripheral arterial thrombosis in the nephrotic syndrome. Surgery 114(3):618–623
Mehls O, Andrassy K, Koderisch J, Herzog U, Ritz E (1987) Hemostasis and thromboembolism in children with nephrotic syndrome: differences from adults. J Pediatr 110(6):862–867
Don DM, Ishiyama A, Johnstone AK, Fu YS, Abemayor E (1996) Angiolymphoid hyperplasia with eosinophilia and vascular tumors of the head and neck. Am J Otolaryngol 17:240–245
Crishman E, Wolfe D, Spiera H (1995) Eosinophilic temporal and systemic arteritis. Hum Pathol 26(2):241–244
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Danis, R., Ozmen, S., Akin, D. et al. Thrombosis of temporal artery and renal vein in Kimura disease related nephrotic syndrome. J Thromb Thrombolysis 27, 115–118 (2009). https://doi.org/10.1007/s11239-007-0178-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11239-007-0178-6