Abstract
The present study investigate to what extent basic-clinical collaboration and involvement in translational research improve performance of researchers, in the particular setting of hospitals affiliated with the Spanish National Health System (NHS). We used a combination of quantitative science indicators and perception-based data obtained through a survey of researchers working at NHS hospitals. Although collaborating with clinical researchers and health care practitioners may increase productivity of basic researchers working in clinical settings, the extent to which they are able to contribute to translational research is the factor that allows them to make a qualitative leap in their scientific production in highly ranked international scientific journals. Our results challenge the arguments by some authors that translational projects have more difficulties than basic proposals to be granted by funding agencies and to be published in high-impact journals. Although they are not conclusive, our results point towards the existence of a positive relationship between leadership and involvement in translational research. Basic-clinical collaboration and translational research should be an incentive for researchers as they are likely to favour their performance. Hospitals will benefit from encouraging researchers and health care practitioners to collaborate in the framework of translational projects, as a way to improve not only individual, but institutional research performance. Spanish hospitals should contribute to overcome obstacles to translational research, through the full integration of basic researchers within the hospital setting and the definition of a research career path within the NHS.
Similar content being viewed by others
References
Antonio-García, M. T., López-Navarro, I., & Rey-Rocha, J. (2014). Determinants of success for biomedical researchers. A perception-based study in a health science research environment. Scientometrics, 101, 1747–1779.
Arias, I. M. (2004). Bridge building between medicine and basic science. In Committee on the Evaluation of the Lucille P. Markey Charitable Trust Programs in Biomedical Sciences, Board on Higher Education and Workforce, & National Research Council (Eds.), Bridging the bed-bench gap: Contributions of the Markey Trust (pp. 45–59). Washington, DC: National Academies Press.
Bornstein, S. R., & Licinio, J. (2011). Improving the efficacy of translational medicine by optimally integrating health care academia and industry. Nature Medicine, 17, 1567–1569.
Bosch, X. (2000). Juan Rodés: Pulling basic and clinical research together. The Lancet, 355, 730.
Cripe, T. P., Thomson, B., Boat, T. F., & Willians, D. A. (2005). Promoting translational research in academic health centers: Navigating the “roadmap”. Academic Medicine, 80, 1012–1018.
Drolet, B. C., & Lorenzi, N. M. (2011). Translational research: Understanding the continuum from bench to bedside. Translational Research, 157, 1–5.
Feldman, A. M. (2008). Does academic culture support translational research? Clinical and Translational Science, 1(2), 87–88.
He, Z. L., Geng, X. S., & Campbell-Hunt, C. (2009). Research collaboration and research output: A longitudinal study of 65 biomedical scientists in a New Zealand university. Research Policy, 38, 306–317.
Hobin, J. A., Deschamps, A. M., Bockman, R., Cohen, S., Dechow, P., Eng, C., et al. (2012). Engaging basic scientists in translational research: Identifying opportunities, overcoming obstacles. Journal of Translational Medicine, 10, 72.
Hörig, H., Marincola, E., & Marincola, F. M. (2005). Obstacles and opportunities in translational research. Nature Medicine, 11(7), 705–708.
Joiner, K. A. (2005). The not-for-profit form and translational research: Kerr revisited? Journal of Translational Medicine, 3, 19.
Katz, J. S. (1994). Geographical proximity and scientific collaboration. Scientometrics, 31(1), 31–43.
Katz, J. S., & Martin, B. R. (1997). What is research collaboration? Research Policy, 26, 1–18.
Lander, B., & Atkinson-Grosjean, J. (2011). Translational science and the hidden research system in universities and academic hospitals: A case study. Social Science and Medicine, 72, 537–544.
Lee, K., Brownstein, J. S., Mills, R. G., & Kohane, I. S. (2010). Does collocation inform the impact of collaboration? PLoS One, 5(12), e14279.
Lee, L. S., Pusek, S. N., McCormack, W. T., Helitzer, D. L., Martina, C. A., Dozier, A., et al. (2012). Clinical and translational scientist career success: Metrics for evaluation. Clinical and Translational Science, 5(5), 400–407.
Littman, B. H., Di Mario, L., Plebani, M., & Marincola, F. M. (2007). What’s next in translational medicine? Clinical Science, 112, 217–227.
Mâsse, L. C., Moser, R. P., Stokols, D., Taylor, B. K., Marcus, S. E., Morgan, G. D., et al. (2008). Measuring collaboration and transdisciplinary integration in team science. American Journal of Preventive Medicine, 35(2S), S151–S160.
Pozen, R., & Kline, H. (2011). Defining success for translational research organizations. Science Translational Medicine, 3(94), 94cm20.
Rey-Rocha, J., & López-Navarro, I. (2014). The fourth mission of hospitals and the role of researchers as innovation drivers in the public healthcare sector. Revista Española de Documentación Científica, 37(1), e028.
Rey-Rocha, J., & Martín-Sempere, M. J. (2012). Generating favorable contexts for translational research through the incorporation of basic researchers into hospitals. The FIS/Miguel Servet Research Contract Program. Science and Public Policy, 39(6), 787–801.
Rubio, D. M., Schoenbaum, E. E., Lee, L. S., Schteingart, D. E., et al. (2010). Defining translational research: Implications for training. Academic Medicine, 85, 470–475.
Stokols, D., Fuqua, J., Gress, J., Harvey, R., Phillips, K., Baezconde-Garbanati, L., et al. (2003). Evaluating transdisciplinary science. Nicotine and Tobacco Research, 5(Suppl. 1), S21–S39.
Subramanyam, K. (1983). Bibliometric studies of research collaboration: A review. Journal of Information Science, 6, 33–38.
Weber-Main, A. M., Finstad, D. A., Center, B. A., & Bland, C. J. (2013). An adaptive approach to facilitating research productivity in a primary care clinical department. Academic Medicine, 88(7), 1–10.
Acknowledgments
The present study would not have been possible without the contributions of many people. Our thanks go to all researchers who patiently completed the survey. We acknowledge Concepción Murillo, José Manuel Rojo and Mª Ángeles Toribio, from the Statistical Analysis Unit at the Centre for Human and Social Sciences (CCHS-CSIC), and Belén Garzón, for their help with the statistical analysis of the data. We also thank María Bordons and the personnel of the ACUTE research group for facilitating access to their bibliometric database. Our particular thanks go to Joan Comella for his unfailing encouragement to undertake this project. Among colleagues at different institutions who aided us in different phases of the project, we express our particular appreciation to Joaquín Arenas, Manuel Carrasco, Mercedes Dulanto, Fernando Gómez, Isabel Mangas, Álvaro Roldán and the rest of the staff at the Carlos III Health Institute; and Carmen Cotelo, Aurelio Rodriguez and José Vilariño at the Supercomputing Centre of Galicia (CESGA). We are also grateful to the two anonymous reviewers for their valuable comments and suggestions. This work was supported by the Carlos III Health Institute General Subdirectorate for the Evaluation and Promotion of Research, Spanish Ministry of Health, within the framework of the Spanish RDI Plan (Grant Numbers PI10/00462 and PI06/0983).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Rey-Rocha, J., López-Navarro, I. & Antonio-García, M.T. Opening doors to basic-clinical collaboration and translational research will improve researchers’ performance. Scientometrics 105, 2057–2069 (2015). https://doi.org/10.1007/s11192-015-1754-8
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11192-015-1754-8