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Analytical Method of Correction of B 1 Errors in Mapping of Magnetization Transfer Ratio in Highfield Magnetic Resonance Tomography

  • Physics of Magnetic Phenomena
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Russian Physics Journal Aims and scope

Magnetization Transfer Ratio (MTR) is a widely used parameter for quantitative estimation of tissues in magnetic resonance tomography (MRT). At the same time, MTR is rather sensitive to errors caused by the nonideal characteristics of magnetic resonance tomographs. In particular, MTR depends strongly on the local inhomogeneities of the radio-frequency field B 1 that limits the MTR application for high magnetic field strengths. In the present research, a simple analytical model of the MTR dependence on B 1 is derived. Based on this model, a correction algorithm is developed using a set of parameters independent of tissue. This algorithm is tested for MTR mapping of the human brain in the field with induction of 3 T. The MTR correction demonstrates high accuracy for a wide range of B 1 inhomogeneities. Combination of the analytical algorithm with fast B 1 mapping enables high-precision MTR brain mapping for neuroimaging applications and analysis of histograms on high-field scanners.

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Authors and Affiliations

  1. University of Washington, Seattle, USA

    V. L. Yarnykh

  2. National Research Tomsk State University, Tomsk, Russia

    V. L. Yarnykh & M. Yu. Khodanovich

Authors
  1. V. L. Yarnykh
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  2. M. Yu. Khodanovich
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Correspondence to M. Yu. Khodanovich.

Additional information

Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Fizika, No. 12, pp. 146–150, December, 2014.

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Yarnykh, V.L., Khodanovich, M.Y. Analytical Method of Correction of B 1 Errors in Mapping of Magnetization Transfer Ratio in Highfield Magnetic Resonance Tomography. Russ Phys J 57, 1784–1788 (2015). https://doi.org/10.1007/s11182-015-0451-7

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  • DOI: https://doi.org/10.1007/s11182-015-0451-7

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