Skip to main content
Log in

Tris(hydroxymethyl)nitromethane in phospholipids synthesis

  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

The tris(hydroxymethyl)nitromethane acetone derivative was applied as an initial compound for phospholipid syntheses. This ketal was converted in succession into the corresponding O,O- and O,N-cyclophosphites used further for preparation by the methods of organophosphorus chemistry of the first representatives from the following phospholipid types: phosphocholines, phosphomethylcolamines, diol phospholipids, and also cationic phospholipids.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. Predvoditelev, D.A. and Nifant’ev, E.E., Usp. Khim., 1997, vol. 66, p. 47.

    Google Scholar 

  2. Predvoditelev, D.A., Kosarev, G.V., Suvorkin, S.V., and Nifant’ev, E.E., Zh. Org. Khim., 2002, vol. 38, p. 1671.

    Google Scholar 

  3. Predvoditelev, D.A., Malenkovskaya, M.A., and Nifant’ev, E.E., Zh. Obshch. Khim., 2003, vol. 73, p. 1620.

    Google Scholar 

  4. Predvoditelev, D.A. and Nifant’ev, E.E., Zh. Org. Khim., 1995, vol. 31, p. 1761.

    Google Scholar 

  5. Malenkovskaya, M.A., Predvoditelev, D.A., Bel’skii, V.K., and Nifant’ev, E.E., Zh. Obshch. Khim., 2003, vol. 73, p. 1976.

    Google Scholar 

  6. Burchardt, A., Takahashi, T., Takenchi, J., and Haufe, G., J. Org. Chem., 2001, vol. 66, p. 2078.

    Google Scholar 

  7. Shin, J., Qualls, M.M., Boomer, J.A., Babarge, J., and Thompson, D.N., J. Am. Chem. Soc., 2001, vol. 123, p. 508.

    Google Scholar 

  8. Nifantyev, E.E., Predvoditelev, D.A., Malenkovskaya, M.A., Bekker, A.R., and Meshkov, C.V., Phosphorus Sulfur and Silicon, 1994, vol. 89, 199.

    Google Scholar 

  9. Predvoditelev, D.A., Cuvorkin, S.V., and Nifant’ev, E.E., Zh. Obshch. Khim., 2001, vol. 71, p. 930.

    Google Scholar 

  10. Predvoditelev, D.A., Kosarev, G.V., and Nifant’ev, E.E., Zh. Obshch. Khim., 2003, vol. 73, p. 1611.

    Google Scholar 

  11. Li, S. and Huang, L., Gene Ther., 2000, vol. 7, p. 31.

    Google Scholar 

  12. Maslov, M.A., Morozova, N.G., and Serebrennikova, G.A., Izv. Akad. Nauk, Ser. Khim., 2002, vol. 10, p. 1778.

    Google Scholar 

  13. Sokolova, T.V., Klesareva, Yu.S., and Serebrennikova, G.A., Zh. Org. Khim., 2004, vol. 40, p. 365.

    Google Scholar 

  14. Gefter, E.L., Zh. Obshch. Khim., 1956, vol. 26, p. 1440.

    Google Scholar 

  15. Zwierak, A., Canad. J. Chem., 1967, vol. 45, p. 2501.

    Google Scholar 

  16. Lucas, H.J., Mitchel, F.N., and Scally, C.N., J. Am. Chem. Soc., 1950, vol. 72, p. 5491.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Zhurnal Organicheskoi Khimii, Vol. 40, No. 11, 2004, pp. 1728–1734.

Original Russian Text Copyright © 2004 by Predvoditelev, Malenkovskaya, Nifant’ev.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Predvoditelev, D.A., Malenkovskaya, M.A. & Nifant’ev, E.E. Tris(hydroxymethyl)nitromethane in phospholipids synthesis. Russ J Org Chem 40, 1682–1688 (2004). https://doi.org/10.1007/s11178-005-0079-0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11178-005-0079-0

Keywords

Navigation