Abstract
The Amyloid A1 (AA1) and A2 (AA2) proteins, which result from proteolytic cleavage of the Serum Amyloid A1 (SAA1) and A2 (SAA2) proteins, are major protein components of the Amyloid A deposits found in secondary amyloidosis. This study determines frequency of serum amyloid A2 alleles (α, β) in healthy Turkish, Azerbaijani, and Kazakh subjects. Two hundred Turkish, sixty-five Azerbaijani and sixty-five Kazakh healthy individuals were studied by previously described the PCR-RFLP methods. Our data revealed that the frequencies of the α and β alleles at the SAA2 locus in the Turkish healthy population were different when compared to those in Azerbaijani and Kazakh healthy populations (P = 0.014 and 0.02), respectively. In contrast, the difference between α and β alleles at the SAA2 locus was not different in both Kazakh and Azerbaijani healthy populations (P = 0.882).
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From Genetika, Vol. 41, No. 7, 2005, pp. 986–989.
Original English Text Copyright © 2005 by Hakki Tastan, Ozlem Osmanagaoglu, Ayla Tuzun.
The text was submitted by the authors in English.
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Tastan, H., Osmanagaoglu, O. & Tuzun, A. The Frequencies of the Serum Amyloid A2 Alleles in Healthy (Turkish, Azerbaijani, and Kazakh) Populations. Russ J Genet 41, 805–807 (2005). https://doi.org/10.1007/s11177-005-0164-z
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DOI: https://doi.org/10.1007/s11177-005-0164-z