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The Effect of Chromatin Remodeling and Modification on RNA-Polymerase-Mediated Transcription Initiation

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Abstract

As eukaryotes are characterized by the presence of chromatin (intricately packaged DNA), special mechanisms are required for preparing the DNA template for operation of the transcription machinery. Recently, a close association between the chromatin state and transcription was found and numerous transcription factors modifying the physical and chemical chromatin state were revealed. This review presents a brief description of transcription initiation on the DNA template within chromatin.

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Authors and Affiliations

  1. Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia

    Yu. V. Shidlovskii & E. N. Nabirochkina

  2. Center for Medical Research, Oslo University, Moscow, 119334, Russia

    E. N. Nabirochkina

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  1. Yu. V. Shidlovskii
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__________

Translated from Genetika, Vol. 41, No. 7, 2005, pp. 884–893.

Original Russian Text Copyright © 2005 by Shidlovskii, Nabirochkina.

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Shidlovskii, Y.V., Nabirochkina, E.N. The Effect of Chromatin Remodeling and Modification on RNA-Polymerase-Mediated Transcription Initiation. Russ J Genet 41, 720–727 (2005). https://doi.org/10.1007/s11177-005-0151-4

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  • DOI: https://doi.org/10.1007/s11177-005-0151-4

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