Abstract
The reaction of hydroxylamine and steroid obtained by the condensation of 16α,17α-epoxypregn-5-en-20-one with DMF dimethyl acetal proceeded through the involvement of the epoxide fragment and led to the formation of 3β-hydroxy-4′-hydroxylaminoandrost-5-eno[16,17-b]pyridine l′-N-oxide.
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References
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The work was carried out in accordance with the research plan of the Institute of Organic Chemistry of the RAS.
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Dedicated to Academician of the Russian Academy of Sciences M. P. Egorov on the occasion of his 70th birthday.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, Vol. 73, No. 2, pp. 458–460, February, 2024.
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Komkov, A.V., Menchikov, L.G., Dmitrenok, A.S. et al. Unusual reaction of 16α,17α-epoxypregn-5-en-20-one derivative with hydroxylamine. Russ Chem Bull 73, 458–460 (2024). https://doi.org/10.1007/s11172-024-4153-6
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DOI: https://doi.org/10.1007/s11172-024-4153-6