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Design and synthesis of 2-alkylthio-5-(1,2,4-triazol-1-ylmethyl)-1,3,4-thiadiazoles and their fungicidal activity

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Abstract

The design of 2-alkylthio-5-(1,2,4-triazol-1-ylmethyl)-1,3,4-thiadiazoles was formulated and a three-step synthesis approach was developed, their high fungicidal activity was demonstrated against six species of phytopathogenic fungi in in vitro studies.

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Authors and Affiliations

  1. D. I. Mendeleev University of Chemical Technology of Russia, 9 Miusskaya pl., 125047, Moscow, Russian Federation

    G. V. Tsaplin, A. S. Zolotukhina, E. A. Alekseeva, A. L. Alekseenko & S. V. Popkov

  2. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    A. L. Alekseenko

  3. All-Russian Research Institute of Phytopathology, Vl. 5 ul. Institut, Bol’shie Vyazemy, Odintsovsky District, 143050, Moscow Region, Russian Federation

    S. V. Popkov

Authors
  1. G. V. Tsaplin
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  2. A. S. Zolotukhina
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  3. E. A. Alekseeva
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  4. A. L. Alekseenko
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  5. S. V. Popkov
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Corresponding author

Correspondence to G. V. Tsaplin.

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No human or animal subjects were used in this research.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, Vol. 72, No. 9, pp. 2125–2132, September, 2023.

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Tsaplin, G.V., Zolotukhina, A.S., Alekseeva, E.A. et al. Design and synthesis of 2-alkylthio-5-(1,2,4-triazol-1-ylmethyl)-1,3,4-thiadiazoles and their fungicidal activity. Russ Chem Bull 72, 2125–2132 (2023). https://doi.org/10.1007/s11172-023-4007-7

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  • DOI: https://doi.org/10.1007/s11172-023-4007-7

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