Abstract
An efficient synthesis of (13α)-estrone derivatives containing pyran, isoxazole, or pyrazole moieties on the A-ring was performed based on difluoroborate complexes using the chelate methodology. Difluoroborate complexes were synthesized from (13α)-2-acetyl-3-hydroxyestra-1(10),2,4-trien-17-one.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, Vol. 72, No. 8, pp. 1855–1860, August, 2023.
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Sukhanova, A.A., Prezent, M.A., Fakhrutdinov, A.N. et al. Difluoroborate complexes in the synthesis of heterocyclic (13α)-estrone derivatives modified at the A-ring. Russ Chem Bull 72, 1855–1860 (2023). https://doi.org/10.1007/s11172-023-3969-9
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DOI: https://doi.org/10.1007/s11172-023-3969-9