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A new ursane triterpenoid caffeic acid ester from Crataegus oresbia

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Abstract

A new ursane triterpenoid caffeic acid ester, cratoresbate A, together with seven known ursane triterpenoids (3-O-trans-p-coumaroyltormentic acid, 3-O-cis-p-coumaroyltormentic acid, α-amyrin, ursolic acid, pomolic acid, euscaphic acid, and tormentic acid) were isolated from the twigs and leaves of Crataegus oresbia W. W. Sm. Cratoresbate A showed significant cytotoxicity against HepG2 cells with IC50 value of 1.9 µmol L−1.

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Correspondence to Bei Jiang or Chao-Jiang Xiao.

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The authors declare no competing interests.

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This work was financially supported by the National Natural Science Foundation of China (grant No. 82260680), the Yunnan Fundamental Research Projects (grant No. 202201AT070005), the Yunnan Key Laboratory of Screening and Research on Anti-pathogenic Plant Resources from Western Yunnan (grant No. 202105AG070003), the Special Basic Cooperative Research Programs of Yunnan Provincial Undergraduate Universities’ Association (grant No. 2019FH001-050), and the Scientific Research Initiation Fund of Dali University for Doctor (grant No. KYBS201734).

No human or animal subjects were used in this research.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, Vol. 72, No. 8, pp. 1760–1766, August, 2023.

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Wang, Y., Yang, L., Liang, X. et al. A new ursane triterpenoid caffeic acid ester from Crataegus oresbia. Russ Chem Bull 72, 1760–1766 (2023). https://doi.org/10.1007/s11172-023-3958-z

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  • DOI: https://doi.org/10.1007/s11172-023-3958-z

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