Abstract
A new method for preparation of 4-hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]-triazines using 1-nitro-2-morpholinoethylene and 3-diazo-1,2,4-triazoles is proposed. Antiviral activity against the Coxsackie B3 virus and electrochemical transformations of the prepared compounds are studied.
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This work was performed under financial support of the Russian Science Foundation (Project No. 20-13-00142).
No human or animal subjects were used in this research.
The authors declare no competing interests.
Based on the materials of the V Russian Conference on Medicinal Chemistry with international participation “MedChem-Russia 2021” (May 16–19, 2022, Volgograd, Russia).
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2460–2466, November, 2022.
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Drokin, R.A., Fesenko, E.A., Mozharovskaia, P.N. et al. 4-Hydroxy-3-nitro-1,4-dihydrotriazolo[5,1-c][1,2,4]triazines: synthesis, antiviral activity, and electrochemical characteristics. Russ Chem Bull 71, 2460–2466 (2022). https://doi.org/10.1007/s11172-022-3674-0
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DOI: https://doi.org/10.1007/s11172-022-3674-0