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Synthesis of β-triazolyl sulfones via the reaction of vinyl sulfones with 1,2,4-triazoles under basic conditions

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Abstract

A method was developed for the synthesis of β-triazolyl sulfones from vinylsulfones and 1,2,4-triazoles in the presence of sodium triazolide taken as the base. The reaction was carried out in DMSO at room temperature for 120 h. The target compounds were obtained in 25–89% yields.

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Funding

This work was financially supported by the Russian Science Foundation (Grant No. 19-73-20190).

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russia

    P. S. Radulov, A. V. Mozzhegorov, O. M. Mulina, I. A. Yaremenko, A. I. Ilovaisky & A. O. Terent’ev

  2. All-Russian Research Institute for Phytopathology, 5 ul. Institut, 143050, Bolshie Vyazemy, Moscow Region, Moscow, Russia

    P. S. Radulov, O. M. Mulina, I. A. Yaremenko, A. I. Ilovaisky & A. O. Terent’ev

Authors
  1. P. S. Radulov
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  2. A. V. Mozzhegorov
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  3. O. M. Mulina
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  4. I. A. Yaremenko
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  5. A. I. Ilovaisky
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  6. A. O. Terent’ev
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Corresponding author

Correspondence to A. O. Terent’ev.

Additional information

Dedicated to Academician of the Russian Academy of Sciences V. I. Ovcharenko on the occasion of his 70th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1544–1548, July, 2022.

No human or animal subjects were used in this research.

The authors declare no competing interests.

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Radulov, P.S., Mozzhegorov, A.V., Mulina, O.M. et al. Synthesis of β-triazolyl sulfones via the reaction of vinyl sulfones with 1,2,4-triazoles under basic conditions. Russ Chem Bull 71, 1544–1548 (2022). https://doi.org/10.1007/s11172-022-3562-7

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  • DOI: https://doi.org/10.1007/s11172-022-3562-7

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