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Sorption and cocrystallization binding of ZrIV ions with hydroxyapatite as a promising carrier of medical radionuclide 89Zr

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Abstract

A significant difference in behavior of ZrIV ions during their cocrystallization and sorption binding to hydroxyapatite (HAP) is demonstrated. When the concentration of doping ions exceeds 10−4 mol L−1, a chemical reaction with the formation of amorphous zirconium phosphate and complete dissolution of the sorbent occurs in the system rather than sorption. According to the X-ray diffraction and transmission electron microscopy (TEM) data, a similar reaction is also possible at lower concentrations of zirconium ions. The effect of doping ions on the morphology and structure of HAP is significantly lower for the cocrystallization introduction of Zr. In addition, according to high-resolution TEM data, doping ions can uniformly be distributed over the carrier surface or volume. Therefore, this method of binding method can be recommended for the preparation of a target HAP-Zr complex.

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Authors and Affiliations

  1. Department of Chemistry, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskie Gory, 119991, Moscow, Russian Federation

    A. V. Severin, M. A. Orlova, E. A. Kushnir & A. V. Egorov

  2. Pirogov Russian National Research Medical University, 1 ul. Ostrovityanova, 117997, Moscow, Russian Federation

    M. A. Orlova

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  1. A. V. Severin
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  2. M. A. Orlova
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  3. E. A. Kushnir
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  4. A. V. Egorov
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Correspondence to A. V. Severin.

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The authors declare no competing interests.

Additional information

This work was financially supported by the Russian Foundation for Basic Research (Project No. 19-08-00055) using equipment of the Scientific and Educational Center for Collective Use “Nanochemistry and Nanomaterials.”

No human or animal subjects were used in this research.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 449–456, March, 2022.

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Severin, A.V., Orlova, M.A., Kushnir, E.A. et al. Sorption and cocrystallization binding of ZrIV ions with hydroxyapatite as a promising carrier of medical radionuclide 89Zr. Russ Chem Bull 71, 449–456 (2022). https://doi.org/10.1007/s11172-022-3432-3

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  • DOI: https://doi.org/10.1007/s11172-022-3432-3

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