Skip to main content
SpringerLink
Log in

Conformational changes of high-molecular-weight DNA upon binding to noble metal nanoparticles in solution

  • Full Articles
  • Published:
Russian Chemical Bulletin Aims and scope

Abstract

Changes in the secondary and tertiary structure of DNA upon binding to silver, gold, and palladium nanoparticles (NPs) in solution were studied using UV spectroscopy, viscometry, dynamic light scattering, flow birefringence, and atomic force microscopy. A method for preparation of NP bioconjugates with DNA was developed. The enhancement of optical anisotropy of the macromolecule upon its contacts with metal NPs was detected. The effect of the formed structures on the persistence length of DNA and on the volume effects in the system was analyzed. A mechanism of NP formation upon the reduction of DNA-bound metal ions was proposed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Y. Zhang, T. P. Shareena Dasari, H. Deng, H. Yu, J. Environ. Sci. Health Part C, 2015, 33, 286; DOI: https://doi.org/10.1080/10590501.2015.1055161.

    Article  CAS  Google Scholar 

  2. S. B. Yaqoo, R. Adnan, R. M. R. Khan, M. Rashid, Front. Chem., 2020, 8, 376; DOI: https://doi.org/10.3389/fchem.2020.00376.

    Article  Google Scholar 

  3. V. Pareek, A. Bhargava, R. Gupta, N. Jain, Advanced Science, Engineering and Medicine, 2017, 9, 527; DOI: https://doi.org/10.1166/asem.2017.2027.

    Article  CAS  Google Scholar 

  4. M. Sharifi, F. Attar, A. A. Saboury, K. Akhtari, N. Hooshman, A. Hasan, M. A. El-Sayed, M. Falahatia, J. Control. Release, 2019, 311–312, 170; DOI: https://doi.org/10.1016/j.jconrel.2019.08.032.

    Article  Google Scholar 

  5. J. Comenge, C. Sotelo, F. Romero, O. Gallego, A. Barnadas, T. G.-C. Parada, F. Dominguez, V. F. Puntes, PLOS One, 2012, 7, e47562; DOI: https://doi.org/10.1371/journal.pone.0047562.

    Article  CAS  Google Scholar 

  6. P. Sokolov, R. Ramazanov, V. Rolich, M. Popova, V. Shalygin, N. Kasyanenko, Nanotechnology, 2020, 32, 045604; DOI: https://doi.org/10.1088/1361-6528/abc037.

    Article  Google Scholar 

  7. I. Zhidkov, E. Kurmaev, S. Cholakh, E. Fazio, L. D’Urso, Mendeleev Commun., 2020, 30, 285; DOI: https://doi.org/10.1016/j.mencom.2020.05.007.

    Article  CAS  Google Scholar 

  8. E. Shapovalova, A. Golubova, I. Ananieva, T. Baygildiev, O. Shpigun, Mendeleev Commun., 2019, 29, 702; DOI:https://doi.org/10.1016/j.mencom.2019.11.035.

    Article  CAS  Google Scholar 

  9. M. A. González-López, E. M. Gutiérrez-Cárdenas, C. Sánchez-Cruz, J. F. Hernández-Paz, I. Pérez, J. J. Olivares-Trejo, O. Hernández-González, Cancer Nanotechnology, 2020, 11, 4; DOI: https://doi.org/10.1186/s12645-020-00060-w.

    Article  Google Scholar 

  10. V. Leso, I. Iavicoli, Int. J. Mol. Sci., 2018, 19, 503; DOI:https://doi.org/10.3390/ijms19020503.

    Article  Google Scholar 

  11. P. Srinoi, Y.-T. Chen, V. Vittur, M. D. Marquez, T. R. Lee, Appl. Sci., 2018, 8, 1106; DOI: https://doi.org/10.3390/app8071106.

    Article  Google Scholar 

  12. I. Ullah, K. Khan, M. Sohail, K. Ullah, A. Ullah, S. Shaheen, Int. J. Nanomedicine, 2017, 12, 8735; DOI: https://doi.org/10.2147/IJN.S145085.

    Article  CAS  Google Scholar 

  13. J. Chen, Y. Zhu, C. Wu, J. Shi, Chem. Soc. Rev., 2020, 49, 9057; DOI: https://doi.org/10.1039/D0CS00607F.

    Article  CAS  Google Scholar 

  14. N. Kasyanenko, V. Bakulev, I. Perevyazko, T. Nekrasova, O. Nazarova, A. Slita, Y. Zolotova, E. Panarin, J. Biotechnology, 2016, 236, 78; DOI: https://doi.org/10.1016/j.jbiotec.2016.08.010.

    Article  CAS  Google Scholar 

  15. F. Zhou, Y. Yao, J. Luo, X. Zhang, Y. Zhang, D. Yin, F. Gao, P. Wang, Anal. Chim. Acta, 2017, 969, 8; DOI: https://doi.org/10.1016/j.aca.2017.03.038.

    Article  CAS  Google Scholar 

  16. N. Kasyanenko, A. Andreeva, A. Baryshev, V. Bakulev, M. Likhodeeva, P. Vorontsov-Velyaminov, J. Phys. Chem. B, 2019, 123, 9557; DOI: https://doi.org/10.1021/acs.jpcb.9b0734116N.

    Article  CAS  Google Scholar 

  17. M. Kasyanenko, M. Varshavskii, E. Ikonnikov, E. Tolstyko, R. Belykh, P. Sokolov, V. Bakulev, V. Rolich, K. Lopatko, J. Nanomaterials, 2016, 3237250; DOI: https://doi.org/10.1155/2016/3237250.

  18. N. Kasyanenko, Zhang Qiushi, V. Bakulev, M. Osolodkov, P. Sokolov, V. Demidov, Polymers, 2017, 9, 211; DOI:https://doi.org/10.3390/polym9060211.

    Article  Google Scholar 

  19. C. Fang, Y. Fan, J. M. Kong, G. J. Zhang, L. Linn, S. Rafeah, Sensors and Actuators B: Chemical, 2007, 126, 684; DOI: https://doi.org/10.1016/j.snb.2007.04.031.

    Article  CAS  Google Scholar 

  20. N. A. Kasyanenko, S. A. Prokhorova, E. F. Haya Enriquez, S. S. Sudakova, E. V. Frisman, S. A. Dyachenko, N. A. Smorygo, B. A. Ivin, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 1999, 148, 121; DOI: https://doi.org/10.1016/S0927-7757(98)00599-8.

    Article  CAS  Google Scholar 

  21. N. A. Kasyanenko, N. E. Dyakonova, E. V. Frisman, Molecular Biology, 1989, 23, 975.

    CAS  Google Scholar 

  22. N. A. Kasyanenko, G. Selman-Housein Sosa, V. N. Uversky, E. V. Frisman, Molecular Biology, 1987, 21, 140.

    Google Scholar 

  23. N. A. Kas’yanenko, M. S. Varshavskii, G. S. Simanov, V. M. Bakulev, Aktual’nye Voprosy Biologicheskoi Fiziki i Khimii (Topical Issues of Biological Physics and Chemistry), 2019, 4, 182 (in Russian).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Faculty of Physics, St. Petersburg State University, 3 ul. Ul’yanovskaya, 198504, St. Petersburg, Russian Federation

    N. A. Kasyanenko, A. V. Baryshev & V. M. Bakulev

Authors
  1. N. A. Kasyanenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. V. Baryshev
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. M. Bakulev
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to N. A. Kasyanenko.

Additional information

Based on the Materials of the VIII All-Russian Kargin Conference “Polymers-2020” (November 9–13, 2020, Moscow, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1718–1724, September, 2021.

The authors are grateful to M. Likhodeeva and A. Andreeva, students of the Faculty of Physics, St. Petersburg State University, for assistance in conduction of the experiments. Experimental results were partially obtained using the equipment of the Resource Centers of the St. Petersburg State University.

This paper does not contain descriptions of studies on animals or humans.

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kasyanenko, N.A., Baryshev, A.V. & Bakulev, V.M. Conformational changes of high-molecular-weight DNA upon binding to noble metal nanoparticles in solution. Russ Chem Bull 70, 1718–1724 (2021). https://doi.org/10.1007/s11172-021-3275-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11172-021-3275-3

Key words

Search

Navigation