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2-[1-(Dimethylamino)ethyl]ferrocenylphosphinic acid as an organocatalyst of Michael and Friedel—Crafts reactions

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Abstract

Racemic 2-[1-(dimethylamino)ethyl]ferrocenylphosphinic acid was tested as an organocatalyst in the Michael and Friedel—Crafts reactions. The use of this zwitterion provides 78% conversion in the Michael reaction between cyclohexanone and β-nitrostyrene, and 84% conversion in the Friedel—Crafts reaction between β-nitrostyrene and indole.

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Authors and Affiliations

  1. Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”, 8 ul. Arbuzova, 420088, Kazan, Russian Federation

    R. P. Shekurov, L. H. Gilmanova, A. A. Zagidullin & V. A. Miluykov

Authors
  1. R. P. Shekurov
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  2. L. H. Gilmanova
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  3. A. A. Zagidullin
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  4. V. A. Miluykov
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Corresponding author

Correspondence to R. P. Shekurov.

Additional information

Based on the materials of the report at the II Scientific Conference “Dynamic Processes in the Chemistry of Organo-element Compounds”, dedicated to the 75th anniversary of the Arbuzov Institute of Organic and Physical Chemistry of Kazan Scientific Center of the Russian Academy of Sciences (November 11–13, 2020, Kazan, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1415–1417, July, 2021.

The study was financially supported by the Russian Science Foundation (Project No. 19-73-00297).

The authors are grateful to the Assigned Spectral-Analytical Center FRC “Kazan Scientific Center of the Russian Academy of Sciences” for technical assistance in research.

This paper does not contain descriptions of studies on animals or humans.

The authors declare no competing interests.

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Shekurov, R.P., Gilmanova, L.H., Zagidullin, A.A. et al. 2-[1-(Dimethylamino)ethyl]ferrocenylphosphinic acid as an organocatalyst of Michael and Friedel—Crafts reactions. Russ Chem Bull 70, 1415–1417 (2021). https://doi.org/10.1007/s11172-021-3233-0

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  • DOI: https://doi.org/10.1007/s11172-021-3233-0

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