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Polyphenolic components of knotwood extracts from Abies sibirica

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Russian Chemical Bulletin Aims and scope

Abstract

An extract from the knotwood of Abies sibirica (Siberian fir) was studied by HPLC, NMR spectroscopy, and mass spectrometry with the goal to identify new sources of phytoestrogens, which are promising medicinal agents, and to obtain new representatives of natural compounds of the indicated group. The following compounds were found in the extract and identified: 2-(4-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-4-[1-hydroxy-1-(4-hydroxy-3-methoxy-phenyl)methyl]tetrahydrofuran (1), 5′-(7-hydroxymatairesinyl)-5″-(7‴-hydroxymatairesinol) (2), 2,3-bis(4-hydroxy-3-methoxybenzyl)butane-1,4-diol (3, (−)-secoisolariciresinol), and 3-(4-hydroxy-3-methoxybenzyl)-5-(4-hydroxy-3-methoxyphenyl)-4-(hydroxymethyl)dihydro-furan-2(3H)-one (4). Compound 2 was previously unknown.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    D. E. Tsvetkov, A. S. Dmitrenok, Yu. E. Tsvetkov, V. M. Men’shov & N. E. Nifantiev

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  1. D. E. Tsvetkov
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  2. A. S. Dmitrenok
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  3. Yu. E. Tsvetkov
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  4. V. M. Men’shov
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Correspondence to N. E. Nifantiev.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1356–1362, July, 2021.

The authors are grateful to the Program for the Development of Scientific Schools of the N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences.

This paper does not contain descriptions of studies on animals or humans.

The authors declare no competing interests.

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Tsvetkov, D.E., Dmitrenok, A.S., Tsvetkov, Y.E. et al. Polyphenolic components of knotwood extracts from Abies sibirica. Russ Chem Bull 70, 1356–1362 (2021). https://doi.org/10.1007/s11172-021-3223-2

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