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Hyaluronic acid—curcumin electrospun fibers

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Abstract

Hyaluronic acid (HA)-curcumin electrospun fibers exhibiting antimicrobial, anti-inflammatory, and anti-tumorigenic activity were fabricated. It is shown that a metachromatic complex between HA and curcumin is formed in a water-organic medium, thus stabilizing the electro-spinning process and improving the fiber characteristics. The polymer fibers prepared at a voltage of 26 kV have an average diameter of 0.296 μm (at a fiber diameter distribution from 0.146 to 0.630 μm). These HA-curcumin fibers can be widely used both in regenerative medicine and in the development of drug delivery systems.

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References

  1. J. M. C. Bravo, L. J. V. Gómez, A. S. Medina, Electrospinning for Drug Delivery Systems: Drug Incorporation Techniques. In: Electrospinning — Material, Techniques, and Biomedical Applications, Ed. S. Haider, Intech Open, 2016, p. 141–155.

    Google Scholar 

  2. Š. Zupančič, Acta Pharmaceut., 2019, 69, 131–153.

    Article  Google Scholar 

  3. E. Arkan, A. H. Azandaryani, P. Moradipour, L. Behbood, Curr. Pharm. Biotechnol., 2017, 18, 909–924.

    Article  CAS  Google Scholar 

  4. D.-G. Yu, L.-M. Zhu, K. White, C. Branford-White, Health, 2009, 1, 67–75.

    Article  Google Scholar 

  5. R. L. Fischer, M. G. McCoy, S. A. Grant, J. Mater. Sci.-Mater., 2012, 23, 1645–1654.

    Article  CAS  Google Scholar 

  6. W. H. Park, L. Jeong, M. H. Kim, J.-Y. Jung, B. M. Min, Int. J. Nanom ed., 2014, 9, 5277–5287.

    Article  Google Scholar 

  7. W. Xu, W. Yang, Y. Yang, Biotechnol. Progr., 2009, 25, 1788–1795.

    Article  CAS  Google Scholar 

  8. V. Voinchet, P. Vasseur, J. Kern, Am. J. Clin. Dermatol., 2006, 7, 353–357.

    Article  Google Scholar 

  9. E. H. Kim, J. H. Kim, Textile Sci. Eng., 2016, 53, 75–82.

    Article  CAS  Google Scholar 

  10. V. V. Kiroshka, V. A. Petrova, D. D. Chernyakov, Y. O. Bozhkova, K. V. Kiroshka, Y. G. Baklagina, D. P. Romanov, V. Roman, R. V. Kremnev, Y. A. Skorik, J. Mater. Sci.-Mater., 2016, 28.

  11. C. Hu, R. H. Gong, F. L. Zhou, Int. J. Polym. Sci., 2015, 1–12.

    Google Scholar 

  12. T. Garg, G. Rath, A. K. Goyal, J. Drug Target., 2015, 23, 202–221.

    Article  CAS  Google Scholar 

  13. V. Pillay, C. Dott, Y. E. Choonara, C. Tyagi, L. Tomar, P. Kumar, V. M. K. Ndesendo, J. Nanomater., 2013, 1–22.

    Google Scholar 

  14. R. Seeram, M. Zamani, P. P. Molamma, Int. J. Nanomed., 2013, 8, 2997–3017.

    Article  Google Scholar 

  15. I. Kenji, F. Ryuichi, T. Kataoka, S. Kayukawa, World J. Clinical Onc ology, 2011, 2, 339–343.

    Article  Google Scholar 

  16. B. Li, F. Lu, X. Wei, R. Zhao, Molecules, 2008, 13, 1671–1695.

    Article  CAS  Google Scholar 

  17. E. Shankar, A. Goel, K. Gupta, S. Gupta, Curr. Pharmacol. Rep., 2017, 3, 423–446.

    Article  CAS  Google Scholar 

  18. S. J. Hewlings, D. S. Kalman, Foods, 2017, 6, 92–102.

    Article  Google Scholar 

  19. A. T. Matveev and I. M. Afanasov, Poluchenie nanovolokon metodom elektroformovaniya, Uchebnoe posobie dlya studentov [Fabrication of Nanofibers by Electrospinning. A Teaching Guide], Eds V. V. Avdeev, A. Yu. Alentyev, B. I. Lazoryak, O. N. Shornikova, Moscow State Univ., Moscow, 2010, 83 pp. (in Russian).

  20. A. T. Ponomarenko, A. R. Tameev, V. G. Shevchenko, Russ. Chem. Rev., 2018, 87, 923.

    Article  CAS  Google Scholar 

  21. V. N. Khabarov, P. Y. Boykov, M. A. Selyanin, Hyaluronic Acid: Produ ction, Properties, Application in Biology and Medicine, John Wiley & Sons, 2015, 215.

    Google Scholar 

  22. H. Tobata, T. Sagawa, Photochem. Photobiol. Sci., 2016, 15, 329–333.

    Article  CAS  Google Scholar 

  23. M. D. Schoenberg, R. D. Moore, BBA - Specialized Section on Mucoprot eins and Mucopolysaccharides, 1964, 83, 42–51.

    Article  CAS  Google Scholar 

  24. N. Volpi, F. Maccari, J. Titze, J. Chromatography B, 2005, 820, 131–135.

    Article  CAS  Google Scholar 

  25. J. J. Ahire, D. D. Robertson, A. J. van Reenen, L. M. T. Dicks, Biom ed. Pharmacother., 2017, 86, 143–148.

    Article  CAS  Google Scholar 

  26. M. Seon-Lutz, A.-C. Couffn, S. Vignoud, G. Schlatter, A. Hébraud, C arbohydr. Polym., 2019, 207, 246–287.

    Google Scholar 

  27. G. Chen, J. Guo, J. Nie, G. Ma, Polymer, 2016, 83, 12–19.

    Article  CAS  Google Scholar 

  28. A. Chanda, J. Adhikari, A. Ghosh, S. R. Chowdhury, S. Thomas, P. Datta, P. Saha, Int. J. Biol. Macromol., 2018, 116, 774–785.

    Article  CAS  Google Scholar 

  29. V. A. Petrova, D. D. Chernyakov, D. N. Poshina, I. V. Gofman, D. P. Romanov, A. I. Mishanin, A. S. Golovkin, Y. A. Skorik, Materials, 2019, 12, 2016.

    Article  CAS  Google Scholar 

  30. P. P. Snetkov, T. E. Uspenskaia, M. V. Uspenskaya, K. S. Rzametov, 19 th Intern. Multidisciplinary Sci. GeoConference Surveying Geology and Mining Ecology Management, SGEM-2019, 2019, 19, 175–182.

    Google Scholar 

  31. T. Collins, Biotechniques, 2007, 43, 25–30.

    Article  Google Scholar 

  32. S. Manju, K. Sreenivasan, J. Colloid Interf. Sci., 2011, 359, 318–325.

    Article  CAS  Google Scholar 

  33. J. Li, G. H. Shin, X. Chen, H. J. Park, Food Res. Int., 2015, 69, 202–208.

    Article  CAS  Google Scholar 

  34. Z. Jiang, X. Dong, H. Liu, Y. Wang, L. Zhang, Y. Sun, Reactive and Fu nctional Polymers, 2016, 104, 22–29.

    Article  CAS  Google Scholar 

  35. J. E. Scott, F. Heatley, Proc. Natl. Acad. Sci. USA, 1999, 96, 4850–4855.

    Article  CAS  Google Scholar 

  36. J. E. Scott, C. Cummings, A. Brass, Y. Chen, Biochem. J., 1991, 274, 699–705.

    Article  CAS  Google Scholar 

  37. E. D. Atkins, J. K. Sheehan, Science, 1973, 179, 562–564.

    Article  CAS  Google Scholar 

  38. I. C. Dea, M. R. Moorhouse, Science, 1973, 179, 560–562.

    Article  CAS  Google Scholar 

  39. A. Almond, A. Brass, J. K. Sheehan, J. Mol. Biol., 1998, 284, 1425–143.

    Article  CAS  Google Scholar 

  40. Z. Khan, F. M. Kafiah, H. Z. Shafi, F. Nufaiei, S. A. Furquan, A. Mat in, Int. J. Adv. Engineering and Nano Technology, 2015, 2, 15–22.

    Google Scholar 

  41. H. M. Ibrahim, E. M. R. El-Zairy, Chitosan as a Biomaterial - Structure, Properties, and Electrospun Nanofibers. In: Concepts, Compounds and the Alternatives of Antibacterials, Ed. V. Bobbarala, IntechOpen, 2015, 23 p.

    Google Scholar 

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Authors and Affiliations

  1. ITMO University, 49 Kronverksky prosp., 197101, St. Petersburg, Russian Federation

    P. P. Snetkov, V. E. Sitnikova, M. V. Uspenskaya, S. N. Morozkina & R. O. Olekhnovich

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  1. P. P. Snetkov
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  2. V. E. Sitnikova
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  3. M. V. Uspenskaya
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  4. S. N. Morozkina
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  5. R. O. Olekhnovich
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Correspondence to P. P. Snetkov.

Additional information

This work was financially supported by the Russian Foundation for Basic Research (Project No. 19-33-90098).

Based on the materials of the V Jubilee Interdisciplinary Conference “Molecular and Biological Aspects of Chemistry, Pharmaceutics, and Pharmacology” (September 15–18, 2019, Sudak, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 0596—0600, March, 2020.

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Snetkov, P.P., Sitnikova, V.E., Uspenskaya, M.V. et al. Hyaluronic acid—curcumin electrospun fibers. Russ Chem Bull 69, 596–600 (2020). https://doi.org/10.1007/s11172-020-2804-9

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  • DOI: https://doi.org/10.1007/s11172-020-2804-9

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