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Chemical constituents of the extracts of the knotwood of Pinus roxburghii Sarg. and their antioxidant activity

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Abstract

Chemical composition of the extract from the Pinus roxburghii Sarg. knotwood was studied for the first time. The extracts were obtained by ultrasound assisted sequential extraction of knotwood with hexane, acetone—water (95 : 5, v/v), and water. According to GC-MS analysis, hexane extract was dominated by monoterpenoids amounting to 53.57% and sesquiterpenoids (41.05%). Components of the acetone—water (95 : 5, v/v) extract were isolated, purified by HPLC, and identified by NMR spectroscopy and mass spectrometry as 2,3-bis(4-hydroxy-3-methoxybenzyl)butan-1,4-diol, 3-hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one and 3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one. These compounds demonstrated notable antioxidant capacity determined using the amperometric method.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    D. E. Tsvetkov, A. S. Dmitrenok, Yu. E. Tsvetkov, A. O. Chizhov & N. E. Nifantiev

  2. Chemistry and Bioprospecting Division, Institute of Wood Science and Technology, 18th Cross, Malleshwaram, Bangalore, 560003, India

    R. Kumar

  3. Chemistry and Bioprospecting Division, Forest Research Institute, Dehradun, 248006, India

    R. Devrani & V. K. Varshney

  4. International Analytical Center, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    A. Ya. Yashin & Ya. I. Yashin

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  1. D. E. Tsvetkov
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Corresponding authors

Correspondence to V. K. Varshney or N. E. Nifantiev.

Additional information

The authors are grateful to A. Uniyal and A. K. Singh for their help in obtaining the knotwood extracts and the GC-MS analysis of the hexane extract.

This work was financially supported by the Russian Foundation for Basic Research (Project No. 17-53-45030) and the Department of Science&Technology, New Delhi, India (Project No. INT/RUS/RFBR/P-304).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2298–2306, December, 2019.

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Tsvetkov, D.E., Kumar, R., Devrani, R. et al. Chemical constituents of the extracts of the knotwood of Pinus roxburghii Sarg. and their antioxidant activity. Russ Chem Bull 68, 2298–2306 (2019). https://doi.org/10.1007/s11172-019-2703-0

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