Lipase enzymatic microreactor in polysaccharide hydrogel: structure and properties


An enzymatic microreactor was designed on the basis of sodium alginate hydrogel containing a lipolytic enzyme (Candida rugosa lipase) in the polymer matrix pores. The functional properties of lipase were characterized in polysaccharide hydrogel of different concentrations. The polysaccharide hydrogel matrix was shown to act as a microreactor, where the enzyme retains activity during numerous catalytic cycles and allows designing long-acting drug systems of enzymatic nature.

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Correspondence to Yu. F. Zuev.

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Dedicated to Academician of the Russian Academy of Sciences A. I. Konovalov on the occasion of his 85th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 0400–0404, February, 2019.

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Bogdanova, L.R., Rogov, A.M., Zueva, O.S. et al. Lipase enzymatic microreactor in polysaccharide hydrogel: structure and properties. Russ Chem Bull 68, 400–404 (2019).

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Key words

  • polysaccharide hydrogel
  • lipase
  • immobilization
  • enzymatic catalysis