Russian Chemical Bulletin

, Volume 67, Issue 10, pp 1873–1877 | Cite as

Condensation of 5-hydroxy-2-methyl-4H-pyran-4-one with arylglyoxals. Synthesis and properties of 2-aryl-1-(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-yl)ethane-1,2-diones

  • V. G. Melekhina
  • V. S. Mityanov
  • A. N. Komogortsev
  • B. V. Lichitski
  • A. A. Dudinov
  • V. Z. Shirinian
  • M. M. KrayushkinEmail author


A convenient method was developed for the synthesis of previously unknown 1,2-diketones, based on the condensation of 5-hydroxy-2-methyl-4H-pyran-4-one with arylglyoxals. The study demonstrated the possibility of using these compounds to synthesize nitrogen-containing hetero cyclic systems bearing the 3-hydroxypyran-4-one moiety.

Key words

arylglyoxals 5-hydroxy-2-methyl-4H-pyran-4-one 1,2-diketones 4-dimethylaminopyridine 2,4,5-trisubstituted imidazoles 2,3-substituted quinoxalines 


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • V. G. Melekhina
    • 1
  • V. S. Mityanov
    • 1
    • 2
  • A. N. Komogortsev
    • 1
  • B. V. Lichitski
    • 1
  • A. A. Dudinov
    • 1
  • V. Z. Shirinian
    • 1
  • M. M. Krayushkin
    • 1
    Email author
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation
  2. 2.D. Mendeleev University of Chemical Technology of RussiaMoscowRussian Federation

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