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Russian Chemical Bulletin

, Volume 66, Issue 11, pp 2103–2109 | Cite as

Synthesis of 3,3-bis(2-haloethyl) and 3,3,3′-tris(2-haloethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)

  • T. V. Ternikova
  • G. V. Pokhvisneva
  • G. A. Smirnov
  • P. B. Gordeev
  • S. V. Nikitin
  • O. A. Luk’yanov
Full Article

Abstract

Synthetic procedures towards 3,3-bis(2-haloethyl) and 3,3,3′-tris(2-haloethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) via halogenation of the corresponding 2-hydroxyethyl derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) and iodination of the corresponding 2-bromoethyl derivatives were elaborated. The synthesized compounds are promising NO donors in the living organisms.

Key words

1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) 2-haloethyl derivatives alkylation acylation chlorination bromination iodination 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  • T. V. Ternikova
    • 1
  • G. V. Pokhvisneva
    • 1
  • G. A. Smirnov
    • 1
  • P. B. Gordeev
    • 1
  • S. V. Nikitin
    • 1
  • O. A. Luk’yanov
    • 1
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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