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Structure of the receptor layer in electrochemical immunosensors. Modern trends and prospects of development

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Abstract

Literature data on the modern state and prospects for the development of research in the area of receptor layer immobilization in electrochemical immunosensors were examined and systematized. The first section of the review is devoted to structural features and functions of biological immunoreceptors, viz., antibodies or their fragments. The main methods of antibody immobilization on the working electrode surface are considered in detail in the second section. The prospects for the development of electrochemical immunosensors are discussed in the third section of the review.

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  1. Ural Federal University named after the First President of Russia B. N. Yeltsin, 19 ul. Mira, 620002, Ekaterinburg, Russian Federation

    T. S. Svalova, N. N. Malysheva & A. N. Kozitsina

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  1. T. S. Svalova
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Based on the Materials of the XX Mendeleev Congress on General and Applied Chemistry (September 26—30, 2016, Ekaterinburg, Russia).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 1797—1811, October, 2017.

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Svalova, T.S., Malysheva, N.N. & Kozitsina, A.N. Structure of the receptor layer in electrochemical immunosensors. Modern trends and prospects of development. Russ Chem Bull 66, 1797–1811 (2017). https://doi.org/10.1007/s11172-017-1951-0

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