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Synthesis of (5Z,5´Z)-3,3´-(alkane-α,ω-diyl)bis[5-(2-pyridylmethylidene)-2-methylthio-3,5-dihydro-4H-imidazol-4-ones] and their coordination compounds with copper(ii)

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Abstract

A synthesis of copper(ii) coordination compounds based on the new tetradentate organic ligands from the series of (5Z,5´Z)-3,3´-(alkane-α,ω-diyl)bis[5-(2-pyridylmethylidene)-2-thio-3,5-dihydro-4H-imidazol-4-ones] was suggested. Biological activity of the copper(ii) coordination compounds was studied, their ability to inhibit telomerase activity was shown.

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Authors and Affiliations

  1. Department of Chemistry, M. V. Lomonosov Moscow State University, Build. 3, 1 Leninskie Gory, 119991, Moscow, Russian Federation

    K. I. Tishchenko, E. K. Beloglazkina, M. A. Proskurnin, A. G. Mazhuga, M. E. Muratova, D. A. Skvortsov & N. V. Zyk

Authors
  1. K. I. Tishchenko
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  2. E. K. Beloglazkina
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  3. M. A. Proskurnin
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  4. A. G. Mazhuga
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  5. M. E. Muratova
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  6. D. A. Skvortsov
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  7. N. V. Zyk
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Corresponding author

Correspondence to E. K. Beloglazkina.

Additional information

Dedicated to Academician of the Russian Academy of Sciences O. G. Sinyashin on the occasion of his 60th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1254–1259, May, 2016.

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Tishchenko, K.I., Beloglazkina, E.K., Proskurnin, M.A. et al. Synthesis of (5Z,5´Z)-3,3´-(alkane-α,ω-diyl)bis[5-(2-pyridylmethylidene)-2-methylthio-3,5-dihydro-4H-imidazol-4-ones] and their coordination compounds with copper(ii). Russ Chem Bull 65, 1254–1259 (2016). https://doi.org/10.1007/s11172-016-1444-6

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  • DOI: https://doi.org/10.1007/s11172-016-1444-6

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