Abstract
Tetrasubstituted N´,N´-dibenzylisothioureas were shown to activate AMPA receptors. A number of structural specificities determining activity of the synthesized compounds against NMDA and AMPA receptors were identified.
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Dedicated to Academician of the Russian Academy of Sciences N. S. Zefirov on the occasion of his 80th birthday.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 2189–2194, September, 2015.
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Proshin, A.N., Grigor’ev, V.V., Tikhonova, I.G. et al. Tetrasubstituted thiuronium salts as multitarget compounds affecting brain NMDA and AMPA receptors. Russ Chem Bull 64, 2189–2194 (2015). https://doi.org/10.1007/s11172-015-1137-6
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DOI: https://doi.org/10.1007/s11172-015-1137-6