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Assymmetric Ir-catalyzed hydrogenation of 2-methylindole using phosphite-type ligands

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Abstract

The asymmetric Ir-catalyzed hydrogenation of 2-methylindole using chiral phosphite-type ligands was carried out for the first time. It was shown that the addition of iodine leads to considerable rise of conversion and enantioselectivity.

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation

    D. V. Ozolin, S. E. Lyubimov & V. A. Davankov

Authors
  1. D. V. Ozolin
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  2. S. E. Lyubimov
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  3. V. A. Davankov
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Corresponding author

Correspondence to S. E. Lyubimov.

Additional information

Dedicated to academician of Russian Academy of Sciences Yu. N. Bubnov on his 80th birthday and to A. N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences on its 60th anniversary.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 10, pp. 2399–2401, October, 2014.

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Ozolin, D.V., Lyubimov, S.E. & Davankov, V.A. Assymmetric Ir-catalyzed hydrogenation of 2-methylindole using phosphite-type ligands. Russ Chem Bull 63, 2399–2401 (2014). https://doi.org/10.1007/s11172-014-0754-9

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  • DOI: https://doi.org/10.1007/s11172-014-0754-9

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