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Synthesis, structure, and growth-promoting activity of 1-alkyl-4-(3-naphthyloxyprop-1-ynyl)piperidin-4-ols

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Abstract

Alkylation of 1- and 2-naphthols with propargyl bromide in acetone in the presence of potassium carbonate led to prop-2-ynyloxynaphthalenes, which upon reaction with 1-alkyl-piperidin-4-ones under the Favorsky conditions afforded the corresponding tertiary alcohols. 1-Methyl-4-[3-(2-naphthyloxy)prop-1-ynyl]piperidin-4-ol hydrochloride was found to possess a high growth-promoting activity in the concentration of 0.001% upon the pre-sowing treatment of beetroot seeds and potatoes and increase their productivity by ∼20%.

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Authors and Affiliations

  1. L. N. Gumilyov Eurasian National University, ul. Mirzoyana, 010000, Astana, Republic of Kazakhstan

    M. T. Omirzak & R. Sh. Erkasov

  2. A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1 ul. Favorskogo, 664033, Irkutsk, Russian Federation

    B. G. Sukhov & T. V. Ganenko

Authors
  1. M. T. Omirzak
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  2. R. Sh. Erkasov
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  3. B. G. Sukhov
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  4. T. V. Ganenko
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Corresponding author

Correspondence to M. T. Omirzak.

Additional information

Dedicated to Academician of the Russian Academy of Sciences M. P. Egorov on the occasion of his 60th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2442–2444, Novemer, 2013.

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Omirzak, M.T., Erkasov, R.S., Sukhov, B.G. et al. Synthesis, structure, and growth-promoting activity of 1-alkyl-4-(3-naphthyloxyprop-1-ynyl)piperidin-4-ols. Russ Chem Bull 62, 2442–2444 (2013). https://doi.org/10.1007/s11172-013-0353-1

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  • DOI: https://doi.org/10.1007/s11172-013-0353-1

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