Abstract
Noncatalytic and Cu(I)-catalyzed dipolar cycloadditions of heterocyclic a-nitro azides to substituted alkynes were studied. Catalytic cyclization gave 1,4-disubstituted triazoles only. The effect of the substituents in alkynes and that of the nature of the starting heterocycles on the isomer ratio of triazoles were examined. New representatives of 1,2,3-triazoles were obtained; their physicochemical properties were studied. A comparative analysis of the spectral characteristics of the resulting regioisomeric triazole derivatives was performed.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2098–2107, November, 2012.
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Katorov, D.V., Rudakov, G.F., Katorova, I.N. et al. Synthesis of 1,2,3-triazoles from heterocyclic α-nitro azides. Russ Chem Bull 61, 2114–2123 (2012). https://doi.org/10.1007/s11172-012-0296-y
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DOI: https://doi.org/10.1007/s11172-012-0296-y