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Amphiphilic α-cyclodextrin derivatives containing residues of pharmacologically important acids

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Abstract

New representatives of amphiphilic α-cyclodextrin derivatives containing residues of pharmacologically important acids both at the primary and secondary hydroxyl groups were synthesized using acyl chlorides of palmitic acid and a series of aromatic monocarboxylic acids. The acyl chloride groups were assigned to the positions C(2), C(3), or C(6) of the carbohydrate fragments of α-cyclodextrin by 13C NMR spectroscopy.

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Authors and Affiliations

  1. Department of Chemistry, Moscow Pedagogical State University, 3 Nesvizhsky per., 119021, Moscow, Russian Federation

    M. K. Grachev, A. V. Edunov, G. I. Kurochkina, N. O. Soboleva, L. K. Vasyanina & E. E. Nifant’ev

  2. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    N. O. Soboleva

Authors
  1. M. K. Grachev
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  2. A. V. Edunov
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  3. G. I. Kurochkina
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  4. N. O. Soboleva
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  5. L. K. Vasyanina
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  6. E. E. Nifant’ev
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Correspondence to A. V. Edunov.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 178–184, January, 2012.

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Grachev, M.K., Edunov, A.V., Kurochkina, G.I. et al. Amphiphilic α-cyclodextrin derivatives containing residues of pharmacologically important acids. Russ Chem Bull 61, 181–187 (2012). https://doi.org/10.1007/s11172-012-0025-6

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  • DOI: https://doi.org/10.1007/s11172-012-0025-6

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