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N-Substituted α-trifluoromethyl β-nitro amines in the synthesis of fluorine-containing 1,2-diamines, amino alcohols, and β-amino acids

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Abstract

Reactions of 2-diazo-1,1,1-trifluoro-3-nitropropane or 1-trifluoromethyl-2-nitroethenes with amines and amino alcohols afforded N-mono- and N,N-disubstituted α-trifluoromethyl β-nitro amines, which were used to obtain a number of trifluoromethyl-containing 1,2-diamines, amino alcohols, and β-amino acids.

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Authors and Affiliations

  1. A. M. Gorky Ural State University, 51 prosp. Lenina, 620083, Ekaterinburg, Russian Federation

    V. Yu. Korotaev & I. B. Kutyashev

  2. I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22/20 ul. S. Kovalevskoi, 620041, Ekaterinburg, Russian Federation

    A. Yu. Barkov, M. I. Kodess, P. A. Slepukhin & A. Ya. Zapevalov

Authors
  1. V. Yu. Korotaev
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  2. A. Yu. Barkov
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  3. M. I. Kodess
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  4. I. B. Kutyashev
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  5. P. A. Slepukhin
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  6. A. Ya. Zapevalov
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Corresponding author

Correspondence to V. Yu. Korotaev.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 9, pp. 1827–1838, September, 2009.

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Korotaev, V.Y., Barkov, A.Y., Kodess, M.I. et al. N-Substituted α-trifluoromethyl β-nitro amines in the synthesis of fluorine-containing 1,2-diamines, amino alcohols, and β-amino acids. Russ Chem Bull 58, 1886–1898 (2009). https://doi.org/10.1007/s11172-009-0257-2

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  • DOI: https://doi.org/10.1007/s11172-009-0257-2

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