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Synthesis and antioxidant activity of 7,7,9-trimethyl-6,7-dihydrofuro[3,2-f]quinoline

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Abstract

The method for the synthesis of 7,7,9-trimethyl-6,7-dihydrofuro[3,2-f]quinoline was developed. The parameters characterizing its antioxidant activity, the stoichiometric inhibition factor (f ≈ 3), and the rate constant of the reaction with peroxy radicals (fk 7 = 2.4 · 105 L mol−1 s−1, 60 °C) were determined for the model system of initiated ethylbenzene oxidation. The inhibition stoichiometric factor of furodihydroquinoline is 2, but the colored product formed as a result of its conversion in oxidized hydrocarbons provides the additional inhibition with k 7 = 6.3 · 103 L mol−1 s−1.

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Authors and Affiliations

  1. N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 ul. Kosygina, 119334, Moscow, Russian Federation

    V. A. Kuzmin, L. I. Mazaletskaya & T. D. Nekipelova

  2. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    E. N. Khodot

Authors
  1. V. A. Kuzmin
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  2. L. I. Mazaletskaya
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  3. T. D. Nekipelova
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  4. E. N. Khodot
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Correspondence to T. D. Nekipelova.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2356–2360, November, 2008.

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Kuzmin, V.A., Mazaletskaya, L.I., Nekipelova, T.D. et al. Synthesis and antioxidant activity of 7,7,9-trimethyl-6,7-dihydrofuro[3,2-f]quinoline. Russ Chem Bull 57, 2405–2409 (2008). https://doi.org/10.1007/s11172-008-0343-x

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  • DOI: https://doi.org/10.1007/s11172-008-0343-x

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