Abstract
Effective methods for the synthesis of nonracemic 4- and 2-methoxyphenyl glycerol ethers from nonracemic 3-chloropropanediols and by direct resolution of the racemate, respectively, were developed. Some existing discrepancies related to the to chiroptical properties of their derivatives were eliminated. Both ethers were used to synthesize nonracemic 3-O-aryloxy-1,2-di-O′,O″-palmitoyl glycerols.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2275–2278, November, 2008.
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Bredikhina, Z.A., Novikova, V.G., Efremov, Y.Y. et al. 4(2)-Methoxyphenyl glycerol ethers in the synthesis of nonracemic di-O,O-acylglycerols. Russ Chem Bull 57, 2320–2323 (2008). https://doi.org/10.1007/s11172-008-0328-9
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DOI: https://doi.org/10.1007/s11172-008-0328-9