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Synthesis of substituted 7,8-di(propylsulfonyl)pyrrolo[1,2-a]pyrazines

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Abstract

Heating of pyrazinium salts with E-1,2-dichloro-1,2-di(propylsulfonyl)ethene in chloro-form in the presence of three-fold excess of Et3N regiospecifically gives rise to substituted 7,8-di(propylsulfonyl)pyrrolo[1,2-a]pyrazines in high yields.

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Authors and Affiliations

  1. N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., 119991, Moscow, Russian Federation

    N. E. Dontsova, A. M. Shestopalov & V. P. Litvinov

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  1. N. E. Dontsova
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  2. A. M. Shestopalov
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  3. V. P. Litvinov
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Correspondence to N. E. Dontsova.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 424–426, February, 2008.

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Dontsova, N.E., Shestopalov, A.M. & Litvinov, V.P. Synthesis of substituted 7,8-di(propylsulfonyl)pyrrolo[1,2-a]pyrazines. Russ Chem Bull 57, 434–436 (2008). https://doi.org/10.1007/s11172-008-0069-9

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  • DOI: https://doi.org/10.1007/s11172-008-0069-9

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