Abstract
Substituted 5-aryl-3-ethylidene-3H-pyrrol-2-ones were synthesized by the reaction of the corresponding 4-aryl-4-oxobutanoic acids with ketones in the presence of aminating agents. The conditions of this reaction were developed with the use of both the conventional condensation technique and microwave activation. The structures of the reaction products were con-firmed by elemental analysis, IR spectroscopy, and 1H NMR spectroscopy.
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M. M. Abd-Alla and A. Essawy, Ind. J. Chem., 1977, 15, 523.
M. M. Abd-Alla, E. A. Soliman, and M. W. Osman, Rev. Roum. Chim, 1980, 25, 415.
A. Yu. Yegorova, Izv. Akad. Nauk, Ser. Khim., 2002, 172 [Russ. Chem. Bull., Int. Ed., 2002, 51, 183].
El-Abbady, M. A. Omara, and N. G. Kandil, Rev. Roum. Chim., 1974, 19, 79.
Y. Bocchi and G. P. Gardini, Tetrahedron Lett., 1971, 211.
M. M. Abd-Alla, E. A. Soliman, and A. A. Hamed, Egypt. J. Chem., 1980, 23, 93.
A. Yu. Yegorova, V. A. Sedavkina, and Z. Yu. Timofeeva, Khim. Geterotsikl. Soedin., 2001, 602 [Chem. Heterocycl. Compd., 2001 (Engl. Transl.)].
B. V. Timokhin, V. A. Baranskii, and G. D. Eliseeva, Usp. Khim., 1999, 68, 80 [Russ. Chem. Rev., 1999, 68 (Engl. Transl.)].
N. N. Romanova, P. V. Kudan, and A. G. Gravis, Khim. Geterotsikl. Soedin., 2000, 1308 [Chem. Heterocycl. Compd., 2000 (Engl. Transl.)].
L. F. Tietze and T. Eicher, Reaktionen und Synthesen im organisch-chemischen Praktikum und Forschungslaboratorium, Georg Thieme Verlag, Stuttgart-New York, 1991.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 4, pp. 693–696, April, 2006.
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Yegorova, A.Y., Kamneva, I.E. & Shtykova, L.S. Effective synthesis of 5-aryl-3-ethylidene-3H-pyrrol-2-ones. Russ Chem Bull 55, 718–721 (2006). https://doi.org/10.1007/s11172-006-0319-7
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DOI: https://doi.org/10.1007/s11172-006-0319-7