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Synthesis of fluoro-containing pyrimidinones from hexafluoroacetone(ethoxycarbonylimine)

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Abstract

Cyclocondensation of hexafluoroacetone(ethoxycarbonylimine) with various 1,3-C,N-bisnucleophiles afforded novel bis(trifluoromethyl)pyrimidinones, including fused ones, in preparative yields.

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Authors and Affiliations

  1. Institute of Physiologically Active Compounds, Russian Academy of Sciences, 142432, Chernogolovka, Moscow Region, Russian Federation

    V. B. Sokolov & A. Yu. Aksinenko

Authors
  1. V. B. Sokolov
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  2. A. Yu. Aksinenko
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1474–1478, June, 2005.

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Sokolov, V.B., Aksinenko, A.Y. Synthesis of fluoro-containing pyrimidinones from hexafluoroacetone(ethoxycarbonylimine). Russ Chem Bull 54, 1518–1522 (2005). https://doi.org/10.1007/s11172-005-0439-5

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  • DOI: https://doi.org/10.1007/s11172-005-0439-5

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