Abstract
Condensation of 8-arylidenehexahydroquinazoline-2-thiones with di- and trihydroxybenzenes affords the new heterocyclic system, viz., octahydrochromeno[3,2-i]quinazoline-2(1H)-thiones, in which the substituents in both the chromane and quinazoline rings can be varied over a wide range.
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References
G. P. Ellis and I. M. Lockhart, The Chemistry of Heterocyclic Compounds, J. Wiley—Interscience, New York, 1981, 36.
G. W. Burton and K. U. Ingold, Acc. Chem. Res., 1986, 19, 194.
D. J. Brown, Comprehensive Heterocyclic Chemistry, Ed. A. R. Katritzky, Pergamon, Oxford, 1997, 3, 148.
H. I. El-Subbagh, S. M. Abu-Zaid, M. A. Mahran, F. A. Badria, and A. M. Al-Obaid, J. Med. Chem., 2000, 43, 2915.
S. I. Filimonov and E. I. Vaganova, Khim. Geterotsikl. Soedin., 2003, 263 [Chem. Heterocycl. Compd., 2003, 39 (Engl. Transl.)].
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1456–1460, June, 2005.
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Filimonov, S.I., Filimonova, S.A., Shashkov, A.S. et al. Synthesis of substituted octahydrochromeno[3,2-i]quinazoline-2(1H)-thiones. Russ Chem Bull 54, 1500–1504 (2005). https://doi.org/10.1007/s11172-005-0435-9
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DOI: https://doi.org/10.1007/s11172-005-0435-9