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Synthesis of new derivatives of 5,6,7,8-tetrahydro-1,6-naphthyridines and their pharmacological properties

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Abstract

1,5-Dicarbonyl derivatives of piperidine and tropane were studied in the heterocyclization with hydroxylamine hydrochloride. All the 5,6,7,8-tetrahydro-1,6-naphthyridines obtained exhibit a pronounced analgesic effect.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 251–253, January, 2005.

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Vatsadze, S.Z., Kostochka, M.L., Lezina, V.P. et al. Synthesis of new derivatives of 5,6,7,8-tetrahydro-1,6-naphthyridines and their pharmacological properties. Russ Chem Bull 54, 257–258 (2005). https://doi.org/10.1007/s11172-005-0247-y

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  • DOI: https://doi.org/10.1007/s11172-005-0247-y

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