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Geometrical Configuration of 12,13-Epoxyoctadeca-9,11-dienoic Acid, a Product of the Reaction Catalyzed by Flaxseed Allene Oxide Synthase (CYP74A)

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Abstract

The geometrical configuration of a short-living allene oxide reaction product that arises under the catalysis by flaxseed allene oxide synthase (CYP74A) was studied by NMR spectroscopy. The structure of (9Z, 11E)-12,13-epoxyoctadeca-9,11-dienoic acid was established for it from the results of the nuclear Overhauser effect measurements.

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Abbreviations

AOS:

allene oxide synthase

2D-COSY:

two-dimensional correlation spectroscopy

13-HPOD:

(9Z,11E,13S)-13-hydroperoxyoctadeca-9,11-dienoic acid

NOE:

nuclear Overhauser effect

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Authors and Affiliations

  1. Kazan Institute of Biochemistry and Biophysics, Kazan Scientific Center, Russian Academy of Sciences, P. O. Box 30, Kazan, Tatarstan, 420111, Russia

    N. V. Medvedeva, L. Sh. Mukhtarova & A. N. Grechkin

  2. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Tatarstan, Russia

    Sh. K. Latypov & A. A. Balandina

Authors
  1. N. V. Medvedeva
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  2. Sh. K. Latypov
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  3. A. A. Balandina
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  4. L. Sh. Mukhtarova
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  5. A. N. Grechkin
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Corresponding author

Correspondence to A. N. Grechkin.

Additional information

__________

Translated from Bioorganicheskaya Khimiya, Vol. 31, No. 6, 2005, pp. 659–660.

Original Russian Text Copyright © 2005 by Medvedeva, Latypov, Balandina, Mukhtarova, Grechkin.

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Medvedeva, N.V., Latypov, S.K., Balandina, A.A. et al. Geometrical Configuration of 12,13-Epoxyoctadeca-9,11-dienoic Acid, a Product of the Reaction Catalyzed by Flaxseed Allene Oxide Synthase (CYP74A). Russ J Bioorg Chem 31, 595–596 (2005). https://doi.org/10.1007/s11171-005-0083-8

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  • DOI: https://doi.org/10.1007/s11171-005-0083-8

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