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One‐pot and green synthesis 1H-pyrazolo[1,2-b]phthalazine-5,10-dione and dihydropyrano[3,2-c]chromene derivatives by Fe3O4@SiO2-imine/phenoxy-Cu(II) as an efficient and reusable catalyst

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Abstract

In the current study, magnetite-silica core–shell nanoparticles modified with Cu-salen complex (Fe3O4@SiO2-imine/phenoxy-Cu(II)) was utilized as a heterogeneous catalyst for the one-pot multicomponent synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione and dihydropyrano[3,2-c]chromene derivatives under solvent-free conditions, without using any harmful organic reagents/solvent. The current synthetic protocol demonstrates that the reactions proceeds to completing step, leading to the successful synthesis of high purity compounds. Advantages of this method include easy purification, reusability of the catalyst, green and mild procedure and synthesis of new derivatives in high yields within short reaction time.

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Acknowledgements

We gratefully acknowledge the Research Council of Bu‐Ali Sina University for providing facilities and financial support of this research work.

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Authors and Affiliations

  1. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, 6517838683, Hamedan, Iran

    Milad Nesarvand, Davood Azarifar & Hakimeh Ebrahimiasl

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  1. Milad Nesarvand
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  2. Davood Azarifar
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  3. Hakimeh Ebrahimiasl
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Correspondence to Hakimeh Ebrahimiasl.

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Nesarvand, M., Azarifar, D. & Ebrahimiasl, H. One‐pot and green synthesis 1H-pyrazolo[1,2-b]phthalazine-5,10-dione and dihydropyrano[3,2-c]chromene derivatives by Fe3O4@SiO2-imine/phenoxy-Cu(II) as an efficient and reusable catalyst. Res Chem Intermed 47, 3629–3644 (2021). https://doi.org/10.1007/s11164-021-04498-4

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