Biosynthesis of TiO2 nanoparticles using Justicia gendarussa leaves for photocatalytic and toxicity studies
- 62 Downloads
Eco-friendly biosynthesis of polycrystalline titanium dioxide (TiO2) nanoparticles (NPs) was synthesised using Justicia gendarussa (J. gendarussa) leaf extract as oxidizing agents. They were compared with TiO2 NPs synthesized using the glacial acetic acid and also studied was the combined effect of synthesis of TiO2 NPs. The crystalline nature and structural formation of TiO2 NPs synthesized by different methods were confirmed by the X-ray diffraction technique, and functional groups of materials were confirmed by FT-IR spectroscopy. The synthesized materials were investigated for photocatalytic activity for methylene blue under UV irradiation and toxicity activity against MCF-7 and MDA-MB-231 cells. The result indicates that TiO2 NPs synthesised by J. gendarussa showed superior and enhanced activity against MCF-7 and MDA-MB-231. Biosynthesized TiO2 NPs showed higher photodegradation of dyes when compared with other TiO2 NPs synthesized by different methods. This is due to the alterations in band gap; structural changes and surface area in nanoparticles that increased the activity. Also, nanosphere/disc like morphology of TiO2 NPs is confirmed using TEM.
KeywordsJ. gendarussa MCF-7 Photodegradation Titanium dioxide Toxicity
The authors would like to express gratitude to the Indian Nanoelectronics User Program, Department of Electrical and Electronics, Indian Institute of Technology Bombay, for providing financial support and analytical facilities.
The fresh fully matured leaves of J. gendarussa were collected from Nehru Memorial College, Campus and Puthanampatti; India. TiO2 NPs were characterized using HRTEM and FESEM spectroscopy. TiO2 NPs performed methylene blue dye degradation properties. All authors approved the final manuscript.
Compliance with ethical standards
Conflict of interests
The authors declare that they have no conflict of interests.
- 1.M.K. Balaji, K.M. Gothandam. Arch. J. Biol. Technol. 59, e16150529 (2016)Google Scholar
- 8.H. Nosrati, M. Salehiabar, S. Davaran, H. Danafar, H.K. Manjili, Drug Dev. Ind. Pharm. 44, 6 (2017)Google Scholar
- 13.H. Lotfian, F. Nemati, J. IIOABJ. 7, 4 (2016)Google Scholar
- 16.M.I. Setyawati, C.Y. Tay, S.L. Chia, S.L. Goh, W. Fang, M.J. Neo, H.C. Chong, S.M. Tan, S.C. Loo, K.W. Ng, N.S. Tan, D.T. Leong, Nat. Commun. 10, 1 (2013)Google Scholar
- 21.L.Sri, E.W. Prajogo, H. Aucky. In: Symposium of association of medicine natural product researcher 9t, Yogyakarta. (1997)Google Scholar
- 23.S. Lu, G. Zhang, J. Nat. Prod. Research Fomerly Nat. Prod. Lett. 22, 1610 (2008)Google Scholar
- 25.P. Sonala, K. Nayanab, S. Bakulab, S. Mamtab, Int. J. Pharm. Sci. Rev. Res. 10, 116 (2011)Google Scholar
- 26.Z. Ayoba, A.A. Samada, S.M. Boharia, Jurnal Teknologi Sciences & Engineering 64, 45 (2013)Google Scholar
- 27.J. Dasadiaa, V. Vyasa, S. Patela, M. Zaveria, J. Pharm. Sci. Bioscientific Res. 6, 660 (2016)Google Scholar
- 29.S.D. Moodley, A. McMaster, R. Mothilal, J. Cancer Res. 1 (2013)Google Scholar
- 41.H. Nosrati, M. Salehiabar, H. Kheiri Manjili, H. Danafar, S. Davaran, Int. J. Biol. Macromol. 115, 83 (2017)Google Scholar
- 45.N. Singh, B. Manshian, G.J. Jenkins, S.M. Griffiths, P.M. Williams, Maffeis Nano Genotoxicol. Biomater. 30, 3891 (2009)Google Scholar
- 46.M. Rezaei-Tavirani, E. Dolat, H. Hasanzadeh, S.S. Seyyedi, V. Semnani, S. Sobhi, Iran. J. Cancer Prev. (Suppl 6), 37 (2013)Google Scholar