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Saccharose as a new, natural, and highly efficient catalyst for the one-pot synthesis of 4,5-dihydropyrano[3,2-c]chromenes, 2-amino-3-cyano-4H-chromenes, 1,8-dioxodecahydroacridine, and 2-substituted benzimidazole derivatives

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Abstract

Saccharose was applied as a green and natural catalyst for the one-pot, three-component condensation between aromatic aldehydes, malononitrile, and resorcinol, or 4-hydroxycoumarine to afford the corresponding pyran-annulated heterocyclic systems. This green methodology offers several advantages such as the use of a non-hazardous catalyst, easy access, clean work-up, excellent yields, short reaction time, and environmentally mild conditions. In addition, 1,8-dioxodecahydroacridine and 2-substituted benzimidazole derivatives have been synthesized from commercially available starting materials, arylaldehydes, dimedone, amines, or ammonium acetate and o-phenylenediamine using the mentioned catalyst.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran

    Malek Taher Maghsoodlou, Nourallah Hazeri, Fereshteh Nejad Shahrokhabadi, Behzad Naghshbandi, Mohammad Saeed Kazemi-doost, Mahnaz Rashidi, Fatemeh Mir, Mehrnoosh Kangani & Sajjad Salahi

  2. Faculty of Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Esfahān, Iran

    Mojtaba Lashkari

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  1. Malek Taher Maghsoodlou
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Correspondence to Malek Taher Maghsoodlou.

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Maghsoodlou, M.T., Hazeri, N., Lashkari, M. et al. Saccharose as a new, natural, and highly efficient catalyst for the one-pot synthesis of 4,5-dihydropyrano[3,2-c]chromenes, 2-amino-3-cyano-4H-chromenes, 1,8-dioxodecahydroacridine, and 2-substituted benzimidazole derivatives. Res Chem Intermed 41, 6985–6997 (2015). https://doi.org/10.1007/s11164-014-1793-4

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