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An efficient synthesis of 1-thioamidoalkyl-2-naphthol derivatives

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Abstract

The discovery and development of phosphorus pentoxide supported on silica gel (P2O5–SiO2) as an efficient catalyst has led to an efficient method for the direct preparation of 1-thioamidoalkyl-2-naphthol derivatives in high yields by one-pot, three-component reaction of β-naphthol, aryl aldehydes, and thiourea or N-phenylthiourea at 100 °C under solvent-free conditions. In addition to its simplicity, this method has the ability to prepare a wide variety of the desired products.

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Acknowledgments

We are grateful to the University of Sistan and Baluchestan Research Council for partial support of this research.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, PO Box 98135-674, Zahedan, Iran

    Hamid Reza Shaterian, Kobra Azizi & Nafiseh Fahimi

Authors
  1. Hamid Reza Shaterian
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  2. Kobra Azizi
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  3. Nafiseh Fahimi
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Correspondence to Hamid Reza Shaterian.

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Shaterian, H.R., Azizi, K. & Fahimi, N. An efficient synthesis of 1-thioamidoalkyl-2-naphthol derivatives. Res Chem Intermed 40, 2613–2620 (2014). https://doi.org/10.1007/s11164-013-1114-3

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  • DOI: https://doi.org/10.1007/s11164-013-1114-3

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