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Microwave-assisted synthesis of novel fluorinated 1,2,4-triazole derivatives, and study of their biological activity

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Abstract

Microwave irradiation was used for synthesis of a series of novel fluorinated 1,2,4-triazole derivatives. The molecular structures of the compounds were determined by use of 1H NMR and FTIR spectroscopy and MS and HRMS. Study of their biological activity showed most of the compounds had good herbicidal activity.

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References

  1. X.H. Liu, W.G. Zhao, B.L. Wang, Z.M. Li, Res. Chem. Intermed. 38, 1999 (2012)

    Article  CAS  Google Scholar 

  2. X.H. Liu, J.Q. Weng, C.X. Tan, Asian J. Chem. 23, 4064 (2011)

    CAS  Google Scholar 

  3. X.H. Liu, L. Pan, Y. Ma, J.Q. Weng, C.X. Tan, Y.H. Li, Y.X. Shi, B.J. Li, Z.M. Li, Y.G. Zhang, Chem. Biol. Drug Des. 78, 689 (2011)

    Article  CAS  Google Scholar 

  4. X.H. Liu, C.X. Tan, J.Q. Weng, Phosphorus, Sulfur Silicon Relat. Elem. 186, 552 (2011)

    Article  CAS  Google Scholar 

  5. C.X. Tan, J.Q. Weng, Z.X. Liu, X.H. Liu, W.G. Zhao, Phosphorus, Sulfur Silicon Relat. Elem. 187, 990 (2012)

    Article  CAS  Google Scholar 

  6. C.X. Tan, Y.X. Shi, J.Q. Weng, X.H. Liu, B.J. Li, W.G. Zhao, Lett. Drug Des. Discov. 9, 431 (2012)

    Article  CAS  Google Scholar 

  7. X.H. Liu, L. Pan, J.Q. Weng, C.X. Tan, Y.H. Li, B.L. Wang, Z.M. Li, Mol. Divers. 16, 251 (2012)

    Article  CAS  Google Scholar 

  8. C.X. Tan, Y.X. Shi, J.Q. Weng, X.H. Liu, B.J. Li, W.G. Zhao, J. Heterocycl. Chem. (2013) doi: 10.1002/jhet.1656

  9. X.H. Liu, C.X. Tan, J.Q. Weng, Phosphorus, Sulfur Silicon Relat. Elem. 186, 558 (2011)

    Article  CAS  Google Scholar 

  10. N.N. Su, Y. Li, S.J. Yu, X. Zhang, X.H. Liu, W.G. Zhao, Res. Chem. Intermed. 39, 759 (2013)

    Article  CAS  Google Scholar 

  11. S. Li, C. Cui, M.Y. Wang, S.J. Yu, Y.X. Shi, X. Zhang, Z.M. Li, W.G. Zhao, B.J. Li, J. Fluorine Chem. 137, 108 (2012)

    Article  CAS  Google Scholar 

  12. L. Jafri, F.L. Ansari, M. Jamil, S. Kalsoom, S. Qureishi, B. Mirza, Chem. Biol. Drug Des. 79, 950 (2012)

    Article  CAS  Google Scholar 

  13. X.D. Yang, J. Chem. Res. (s) 9, 489 (2008)

    Article  Google Scholar 

  14. B. Mirza, M. Sargordan, azaeli, Asian J. Chem. 24, 1421 (2012)

    CAS  Google Scholar 

  15. V. Niraimathi, A.J. Suresh, T. Latha, Asian J. Chem. 23, 4563 (2011)

    CAS  Google Scholar 

  16. D.J. Ye, Asian J. Chem. 22, 1503 (2010)

    CAS  Google Scholar 

  17. X.H. Liu, L. Pan, C.X. Tan, J.Q. Weng, B.L. Wang, Z.M. Li, Pest. Biochem. Physiol. 101, 143 (2011)

    Google Scholar 

  18. X.H. Liu, P.Q. Chen, B.L. Wang, Y.H. Li, S.H. Wang, Z.M. Li, Bioorg. Med. Chem. Lett. 17, 3784 (2007)

    Google Scholar 

Download references

Acknowledgments

This work was supported financially by the National Natural Science Foundation of China (no. 21002090), the Key Innovation Team of Science and Technology in Zhejiang Province (2010R50018-06), and the National Key Technologies R&D Program (2011BAE06B03-01).

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Authors and Affiliations

  1. College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou, 310014, China

    Xing-Hai Liu, Jian-Quan Weng & Cheng-Xia Tan

  2. State Key Laboratory of Elemento-Organic Chemistry, National Pesticidal Engineering Centre, Nankai University, Tianjin, 300071, China

    Bao-Lei Wang, Yong-Hong Li & Zheng-Ming Li

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  1. Xing-Hai Liu
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  2. Jian-Quan Weng
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  3. Bao-Lei Wang
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  4. Yong-Hong Li
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  5. Cheng-Xia Tan
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  6. Zheng-Ming Li
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Correspondence to Xing-Hai Liu.

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Liu, XH., Weng, JQ., Wang, BL. et al. Microwave-assisted synthesis of novel fluorinated 1,2,4-triazole derivatives, and study of their biological activity. Res Chem Intermed 40, 2605–2612 (2014). https://doi.org/10.1007/s11164-013-1113-4

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  • DOI: https://doi.org/10.1007/s11164-013-1113-4

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