Abstract
Photoirradiation of Me2CO–H2O solution of pent-4-en-1-ol (1a) with a high-pressure mercury lamp in a test tube gave 8-hydroxyoctan-2-one (3a) in 66 % yield along with oxetane (4a) and the isomer (4a′) in 10 % yield. Irradiation of the running Me2CO–H2O solution of 1a in the flow system of a microchannel reactor (MCR) gave mainly 4a. The photoreaction of 1,1-diphenylethene (2a) with triethylamine gave a Markovnikov-type adduct (5a) and an anti-Markovnikov-type adduct (6a). The use of the MCR enhanced the production of 5a. These phenomena were explained by the light-path length effects of the MCR.
Similar content being viewed by others
References
J. Matsumoto, Y. Yoshinaga, A. Hamasaki, T. Kawasaki, T. Yamashita, T. Shiragami, M. Yasuda, Bull. Chem. Soc. Jpn. 84, 1130 (2011)
S. Suga, A. Nagai, J. Yoshida, Chem. Commun. 354 (2003)
Y. Matsushita, N. Ohba, S. Kumada, T. Suzuki, T. Ichimura, Catal. Commun. 8, 2194 (2007)
H. Mukae, H. Maeda, S. Nashihara, K. Mizuno, Bull. Chem. Soc. Jpn. 80, 1157 (2007)
J. Tsuji, M. Kaito, T. Takahashi, Bull. Chem. Soc. Jpn. 51, 547 (1978)
G. Bianchinia, M. Crucianellia, C. Canevalib, C. Crestinic, F. Morazzonib, R. Saladinod, Tetrahedron 62, 12326 (2006)
K. Sato, M. Aoki, J. Takagi, K. Zimmermann, R. Noyori, Bull. Chem. Soc. Jpn. 72, 2287 (1999)
C. Peppe, E.S. Lang, G.N. Ledesma, L.B. Castro, O.S.R. Barros, P.A. Mello, Synlett. 3091 (2005)
I.F. Belskii, Z.K. Minashkina, Russ. Chem. Bull. 19, 2195 (1970)
T. Yamashita, M. Yasuda, M. Watanabe, R. Kojima, K. Tanabe, K. Shima, J. Org. Chem. 61, 6438 (1996)
T. Yamashita, K. Shiomori, M. Yasuda, K. Shima, Bull. Chem. Soc. Jpn. 64, 366 (1991)
W.D. Hounshell, D.A. Dougherty, J.P. Hummel, K. Mislow, J. Am. Chem. Soc. 99, 1916 (1977)
K.G. Stirk, H.I. Kenttamaa, J. Am. Chem. Soc. 113, 5880 (1991)
W. Reusch, J. Org. Chem. 27, 1882 (1962)
S.H. Schroeter, Liebigs Ann. Chem. 1890 (1974)
P.G. Gassman, J.L. Smith, J. Am. Chem. Soc. 48, 4439 (1983)
K.M. Majerski, D. Pavlovic, M.S. Kulyk, J. Org. Chem. 58, 252 (1993)
T. Yamashita, M. Watanabe, R. Kojima, T. Shiragami, K. Shima, M. Yasuda, J. Photochem. Photobiol. A Chem. 118, 165 (1998)
Y. Shiraishi, D. Tsukamoto, T. Hirai, Org. Lett. 10, 3117 (2008)
G. Büchi, C.G. Inman, E.S. Lipinsky, J. Am. Chem. Soc. 76, 4327 (1954)
G.J. Kavarnos, N.J. Turro, Chem. Rev. 86, 401 (1986)
R.S. Ruoff, K.M. Kadish, P. Boulas, E.C.M. Chen, J. Phys. Chem. 99, 8843 (1995)
D. Rehm, A. Weller, Isr. J. Chem. 8, 259 (1970)
S. Toki, H. Shintaro, S. Takamuku, H. Sakurai, Nippon Kagaku Kaishi. 152 (1984)
F.D. Lewis, T.-I. Ho, J. Am. Chem. Soc. 99, 7991 (1977)
F.D. Lewis, D.M. Bassani, J. Photochem. Photobiol. A Chem. 81, 13 (1994)
T. Yamashita, T. Tsurusako, N. Nakamura, M. Yasuda, K. Shima, Bull. Chem. Soc. Jpn. 66, 857 (1993)
D.D.M. Wayner, L. Gravelle, Tetrahedron Lett. 29, 431 (1988)
H. Hailesa, J. Behrendtb, in Comprehensive Heterocyclic Chemistry III, vol. 2, ed. by A. Katritzky, C. Ramsden, E. Scriven, R. Taylor (Elsevier, Amsterdam, 2008), pp. 321–364
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yamashita, T., Matsushita, S., Nagatomo, T. et al. Controlling the photochemical reactions of alkenes by light-path length effects of a microchannel reactor. Res Chem Intermed 39, 111–126 (2013). https://doi.org/10.1007/s11164-012-0636-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11164-012-0636-4