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Using Speckle Dynamics for Comparison of the Metabolic Activity of Different Cell Cultures

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Radiophysics and Quantum Electronics Aims and scope

The dynamics of speckles in the image plane of a monolayer of cells cultivated on a glass substrate has been recorded. Cell cultures HEL-3, L-41, and Vero were selected as the objects of research. The digitized value of the radiation intensity I in one pixel and the parameter η characterizing the change in the intensity distribution on an 10 × 10 pixel area was recorded for 24 hours. The multiple determinacy coefficient of three cell cultures, which was obtained from the time dependences of η, was equal to 0.94.

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Authors and Affiliations

  1. Ural Federal University, Yekaterinburg, Russia

    A. P. Vladimirov, A. S. Malygin, Yu. A. Mikhailova & E. M. Borodin

  2. Yekaterinburg Research Institute of Viral Infections, Rospotrebnadzor, Yekaterinburg, Russia

    A. P. Vladimirov, Yu. A. Mikhailova, A. A. Bakharev & A. P. Poryvaeva

Authors
  1. A. P. Vladimirov
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  2. A. S. Malygin
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  3. Yu. A. Mikhailova
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  4. E. M. Borodin
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  5. A. A. Bakharev
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  6. A. P. Poryvaeva
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Corresponding author

Correspondence to Yu. A. Mikhailova.

Additional information

Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Radiofizika, Vol. 57, No. 8, pp. 654–659, August–September 2014.

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Vladimirov, A.P., Malygin, A.S., Mikhailova, Y.A. et al. Using Speckle Dynamics for Comparison of the Metabolic Activity of Different Cell Cultures. Radiophys Quantum El 57, 584–588 (2015). https://doi.org/10.1007/s11141-015-9542-0

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  • DOI: https://doi.org/10.1007/s11141-015-9542-0

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