Skip to main content

Table 2 Utility decrements for Dutch version of the QLU-C10D

From: Dutch utility weights for the EORTC cancer-specific utility instrument: the Dutch EORTC QLU-C10D

Parameter Severity level Parameter estimatesa Raw utility decrements Decrements with adjustment for monotonicity of levels
α Β Estimate (β/α) SE Estimate SE
Time   0.461      
Physical functioning (restrictions) 1 (not at all)   REF 0 0
2 (a little)   − 0.017 − 0.037 0.024 − 0.036 0.024
3 (quite a bit)   − 0.057 − 0.123** 0.024 − 0.121** 0.024
4 (very much)   − 0.107 − 0.232** 0.021 − 0.228** 0.020
Role functioning (restrictions) 1 (not at all)   REF 0 0
2 (a little)   − 0.007 − 0.016 0.021 − 0.015 0.021
3 (quite a bit)   − 0.053 − 0.116** 0.021 − 0.110** 0.020
4 (very much)   − 0.071 − 0.155** 0.019 − 0.149** 0.018
Social functioning (restrictions) 1 (not at all)   REF 0 0
2 (a little)   − 0.001 − 0.002 0.019 − 0.003 0.019
3 (quite a bit)   − 0.028 − 0.061** 0.019 − 0.059** 0.019
4 (very much)   − 0.048 − 0.105** 0.017 − 0.102** 0.017
Emotional functioning (restrictions) 1 (not at all)   REF 0 0
2 (a little)   0.002 0.003 0.020 0.000
3 (quite a bit)   0.010 0.022 0.022 0.000
4 (very much)   − 0.034 − 0.074** 0.018 − 0.083** 0.015
Pain 1 (not at all)   REF 0 0
2 (a little)   0.003 0.006 0.020 0.000
3 (quite a bit)   − 0.042 − 0.092** 0.020 − 0.095** 0.018
4 (very much)   − 0.112 − 0.243** 0.020 − 0.242** 0.019
Fatigue 1 (not at all)   REF 0 0
2 (a little)   − 0.003 − 0.007 0.018 − 0.005 0.016
3 (quite a bit)   − 0.001 − 0.001 0.020 − 0.005 0.016
4 (very much)   − 0.025 − 0.054** 0.017 − 0.055** 0.016
Sleep 1 (not at all)   REF 0 0
2 (a little)   − 0.026 − 0.056** 0.017 − 0.051** 0.017
3 (quite a bit)   − 0.030 − 0.066** 0.019 − 0.053** 0.016
4 (very much)   − 0.020 − 0.043* 0.018 − 0.053** 0.016
Appetite loss 1 (not at all)   REF 0 0
2 (a little)   − 0.003 − 0.007 0.019 − 0.005 0.019
3 (quite a bit)   − 0.019 − 0.041* 0.020 − 0.035* 0.017
4 (very much)   − 0.011 − 0.025 0.018 − 0.035* 0.017
Nausea 1 (not at all)   REF 0 0
2 (a little)   − 0.015 − 0.033 0.018 − 0.035 0.018
3 (quite a bit)   − 0.036 − 0.078** 0.019 − 0.079** 0.019
4 (very much)   − 0.049 − 0.106** 0.017 − 0.107** 0.017
Bowel problems 1 (not at all)   REF 0 0
2 (a little)   − 0.017 − 0.037 0.019 − 0.038* 0.018
3 (quite a bit)   − 0.019 − 0.041* 0.020 − 0.041* 0.020
4 (very much)   − 0.049 − 0.106** 0.017 − 0.105** 0.017
QIC     18,535.896   18,527.433  
QICC     18,521.158   18,513.676  
  1. QIC Quasi Likelihood under Independence Model Criterion, QICC Corrected Quasi Likelihood under Independence Model Criterion
  2. aParameter estimates obtained from GEE models; α denotes the time parameter and β the health state parameters
  3. *p < 0.05; **p < 0.01